ArticleMedical science monitor : international medical journal of experimental and clinical research2011
Predictors of cardiac hepatopathy in patients with right heart failure.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 36 citations in OpenAlex.
- Do Hemodynamic and Echocardiographic Derangements After the Fontan Operation Correlate with Severity of Liver Disease on Biopsy?Pediatric cardiology · 2026Article
- Review
- Cardiac Hepatopathy: New Perspectives on Old Problems through a Prism of Endogenous Metabolic Regulations by Hepatokines.Antioxidants (Basel, Switzerland) · 2023Review
- Assessment of organ congestion in patients with heart failure by ultrasonography.Journal of echocardiography · 2022Review
- Article
- Morphologic Alterations Precede Functional Hepatic Impairment as Determined byFrontiers in cardiovascular medicine · 2021Article
- Congestive Hepatopathy.International journal of molecular sciences · 2020Review
- Intensive care, right ventricular support and lung transplantation in patients with pulmonary hypertension.The European respiratory journal · 2019Review
- Clinical implications of organ congestion in heart failure patients as assessed by ultrasonography.Cardiovascular diagnosis and therapy · 2018Review
- Histology and Glutamine Synthetase Immunoreactivity in Liver Biopsies From Patients With Congestive Heart Failure.Gastroenterology research · 2017Article
- Safety Profile of Liver FibroScan in Patients with Cardiac Pacemakers or Implantable Cardioverter-Defibrillators.Canadian journal of gastroenterology & hepatology · 2017Article
- Article
- The Genetic Challenges and Opportunities in Advanced Heart Failure.The Canadian journal of cardiology · 2015Review
- Treatment of pulmonary hypertension.Medical science monitor : international medical journal of experimental and clinical research · 2012Review
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSome patients with right heart failure develop cardiac hepatopathy (CH). The pathophysiology of CH is thought to be secondary to hepatic venous congestion and arterial ischemia. We sought to define the clinical and hemodynamic characteristics associated with CH. MATERIAL/
methodsA retrospective cross sectional analysis was performed in which subjects were identified from our institutional cardiology database if echocardiography showed either right ventricular (RV) hypokinesis or dilatation, and was performed within 30 days of right heart catheterization. A chart review was then performed to identify patient clinical characteristics and to determine if the patients had underlying liver disease. Subjects with non-cardiac causes for hepatopathy were excluded.
resultsIn 188 included subjects, etiology for right heart dysfunction included left heart failure (LHF), shunt, pulmonary hypertension, mitral- tricuspid- and pulmonic valvular disease. On multivariate analysis, higher RV diastolic pressure and etiology for RV dysfunction other than LHF were both associated with CH. Low cardiac output was associated with CH only amongst those without LHF.
conclusionsCH is most often seen in subjects with elevated RV diastolic pressure suggesting a congestive cause in most cases. CH associated with low cardiac output in patients without LHF suggests that low flow may be contributing to the patophysiology in some cases.
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