ArticleClinical journal of the American Society of Nephrology : CJASN2011
Association of pretransplant serum phosphorus with posttransplant outcomes.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Pre-Transplant Hyperparathyroidism and Graft or Patient Outcomes After Kidney Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Association of time-updated plasma calcium and phosphate with graft and patient outcomes after kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021Article
- Impact of longer term phosphorus control on cardiovascular mortality in hemodialysis patients using an area under the curve approach: results from the DOPPS.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020Article
- Prediction of Nonadherence and Renal Prognosis by Pre-Transplantation Serum Phosphate Levels.Annals of transplantation · 2019Article
- Mineral metabolism in European children living with a renal transplant: a European society for paediatric nephrology/european renal association-European dialysis and transplant association registry study.Clinical journal of the American Society of Nephrology : CJASN · 2015Article
- Bone and mineral disorders after kidney transplantation: therapeutic strategies.Transplantation reviews (Orlando, Fla.) · 2014Review
- Association of pre-transplant blood pressure with post-transplant outcomes.Clinical transplantation · 2014Article
- Hyperphosphatemia is a combined function of high serum PTH and high dietary protein intake in dialysis patients.Kidney international supplements · 2013Article
- Association of pre-kidney transplant markers of mineral and bone disorder with post-transplant outcomes.Clinical journal of the American Society of Nephrology : CJASN · 2012Article
- Management of mineral and bone disorder after kidney transplantation.Current opinion in nephrology and hypertension · 2012Review
- Mortality associated with dose response of erythropoiesis-stimulating agents in hemodialysis versus peritoneal dialysis patients.American journal of nephrology · 2012Article
- Transplantation: Pretransplantation serum phosphorus level: association with mortality and graft survival.Nature reviews. Nephrology · 2011Article
Corrections and comments
- Commented on by
Authors and funding
9 authors.
Funding
Abstract
BACKGROUND AND
objectivesSerum phosphorus levels are associated with mortality, cardiovascular disease, and renal function loss in individuals with and without chronic kidney disease. The association of pretransplant serum phosphorus levels with transplant outcomes is not clear. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Data of the Scientific Registry of Transplant Recipients (SRTR) up to June 2007 were linked to the database (2001 through 2006) of one of the U.S.-based large dialysis organizations (DaVita). The selected 9384 primary kidney recipients were divided into five groups according to pretransplant serum phosphorus levels (mg/dl): <3.5, 3.5 to <5.5 (reference group), 5.5 to <7.5, 7.5 to <9.5, and ≥9.5. Unadjusted and multivariate adjusted risks for transplant outcomes were compared.
resultsPatients were 48 ± 14 years old and included 37% women and 27% African Americans. After multivariate adjustment, all-cause and cardiovascular death hazard ratios were 2.44 (95% confidence interval: 1.28 to 4.65) and 3.63 (1.13 to 11.64), respectively, in recipients in the ≥9.5 group; allograft loss hazard ratios were 1.42 (1.04 to 1.95) and 2.36 (1.33 to 4.17) in recipients with 7.5 to >9.5 and ≥9.5, respectively. No significant association with delayed graft function was found.
conclusionsPretransplant phosphorus levels 7.5 to <9.5 mg/dl and ≥9.5 mg/dl were associated with increased risk of functional graft failure and increased risk of all-cause and cardiovascular deaths, respectively, when compared with 3.5 to <5.5 mg/dl. Additional studies are needed to examine whether more aggressive control of pretransplant serum phosphorus may improve posttransplant outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.