ArticleNature protocols2011
Primary culture of chick, mouse or human neural crest cells.
Article in Nature protocols, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Contribution of gelsolin and its secretory isoform to the migratory properties of neural crest and DRG cells in the chicken embryo.Frontiers in molecular neuroscience · 2026Article
- An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma.Nature communications · 2023Article
- Glycan Epitope and Integrin Expression Dynamics Characterize Neural Crest Epithelial-to-Mesenchymal Transition (EMT) in Human Pluripotent Stem Cell Differentiation.Stem cell reviews and reports · 2022Article
- Towards Tabula Gallus.International journal of molecular sciences · 2022Review
- Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine.Stem cells translational medicine · 2021Article
- Conversion of mouse embryonic fibroblasts into neural crest cells and functional corneal endothelia by defined small molecules.Science advances · 2021Article
- Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- MESP2 variants contribute to conotruncal heart defects by inhibiting cardiac neural crest cell proliferation.Journal of molecular medicine (Berlin, Germany) · 2020Article
- Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation.Journal of molecular cell biology · 2020Article
- Dissection, Culture and Analysis of Primary Cranial Neural Crest Cells from Mouse for the Study of Neural Crest Cell Delamination and Migration.Journal of visualized experiments : JoVE · 2019Article
- Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation.Oncogenesis · 2019Article
- Establishment of a murine culture system for modeling the temporal progression of cranial and trunk neural crest cell differentiation.Disease models & mechanisms · 2018Article
- Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus.Nature communications · 2018Article
- Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.Nature genetics · 2017Article
- Endoplasmic Reticulum Stress-Induced CHOP Inhibits PGC-1α and Causes Mitochondrial Dysfunction in Diabetic Embryopathy.Toxicological sciences : an official journal of the Society of Toxicology · 2017Article
- Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells.Cell reports · 2016Article
- High glucose environment inhibits cranial neural crest survival by activating excessive autophagy in the chick embryo.Scientific reports · 2015Article
- Cytoplasmic protein methylation is essential for neural crest migration.The Journal of cell biology · 2014Article
- Therapeutic potential of Pnmt+ primer cells for neuro/myocardial regeneration.American journal of stem cells · 2013Review
- Distinct global shifts in genomic binding profiles of limb malformation-associated HOXD13 mutations.Genome research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A highly enriched population of neural crest cells (NCCs) from amniote embryos, such as from chicks, mice and humans, is desirable for experiments in fate determination. NCCs are also useful for testing the functional effects of molecular changes underlying numerous human diseases of neural crest derivatives and for investigating their potential for therapeutic compensation. This protocol details embryonic microdissection followed by neural tube explantation. Conditions favoring NCC expansion and the maintenance of their stem cell-like properties are described. Although neural crest-like cells can be derived from a number of sites in the mature organism, full potential is best ensured by their purification from their source tissue at the outset of migration. Going from embryo to established cell line takes 4 d; the first is the most labor-intensive day, but minimal intervention is required thereafter.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.