ArticleSaudi journal of anaesthesia2011
Intra and postoperative outcome of adding clonidine to bupivacaine in infraorbital nerve block for young children undergoing cleft lip surgery.
Article in Saudi journal of anaesthesia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Infraorbital nerve block for postoperative pain following cleft lip repair in children.The Cochrane database of systematic reviews · 2016Pooled it
- Effect of bilateral infraorbital nerve block on intraoperative anesthetic requirements, hemodynamics, glycemic levels, and extubation in infants undergoing cheiloplasty under general anesthesia.Journal of dental anesthesia and pain medicine · 2021Article
- Updates in Pediatric Regional Anesthesia and Its Role in the Treatment of Acute Pain in the Ambulatory Setting.Current pain and headache reports · 2017Review
- Evaluation of the Efficacy of Bupivacaine (0.5%) alone or with Clonidine (1μg/kg) Versus Control in a Single Level Paravertebral Blockin Patients Undergoing PCNL Procedure.Journal of clinical and diagnostic research : JCDR · 2016Article
- A retrospective analysis of anesthetic experience in 2917 patients posted for cleft lip and palate repair.Anesthesia, essays and researchesArticle
- Effects of bilateral transmucosal sphenopalatine ganglion block on intraoperative anesthetic requirements and recovery profile in children undergoing palatoplasty under general anesthesia.Journal of anaesthesiology, clinical pharmacologyArticle
- The effect of dexmedetomidine added to preemptive (2% lignocaine with adrenaline) infiltration on intraoperative hemodynamics and postoperative pain after ambulatory maxillofacial surgeries under general anesthesia.Anesthesia, essays and researchesArticle
- A comparison of dexamethasone and clonidine as an adjuvant for caudal blocks in pediatric urogenital surgeries.Anesthesia, essays and researchesArticle
- [Ketamine as an adjunct to bupivacaine in infra-orbital nerve block analgesia after cleft lip repair].Brazilian journal of anesthesiology (Elsevier)Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledAIMS AND CONTEXT: To evaluate the efficacy of adding clonidine to bupivacaine in bilateral infraorbital nerve block for hemodynamic changes, requirement of opioids, volatile agent, and muscle relaxants intraoperatively and relief of pain postoperatively SETTING AND
designProspective, randomized, double-blind study.
methodsFifty pediatric patients aged less than 24 months undergoing elective cleft lip repair were randomly allocated to two groups of 25 each. After tracheal intubation, group A received bilateral infraorbital nerve block with 1 ml solution of clonidine (1 μg/kg) and bupivacaine 0.25%, and group B received 1 ml of 0.25% bupivacaine. Hemodynamic parameters, intraoperative requirement of volatile anesthetic agent, muscle relaxant, and analgesic were recorded. Pain was assessed postoperatively using the Face, Legs, Activity, Cry, Consolability scale till the first rescue drug was given. STATISTICAL ANALYSIS: Two sample unpaired t-test and the correlation r test.
resultsThe duration of analgesia from the time of administration of block in group A was 667.72 ± 210.74 min compared to 558.48 ± 150.28 min in group B (P<0.05).
conclusionAddition of clonidine as an adjunct to local anesthetic significantly decreased the requirement of other anesthetic drugs and significantly prolonged the duration of postoperative analgesia without any adverse effects.
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