Evidence map›Paper›PMID 21957222›Full record

ArticleJournal of neurophysiology2011

Long-term patch recordings from adult spinal neurons herald new era of opportunity.

Shawn Hochman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurophysiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Shawn HochmanDepartment of Physiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA. shawn.hochman@emory.edu

Funding

SEROTONIN AND SPINAL REFLEX PLASTICITYR01NS040893 · NINDS · EMORY UNIVERSITY · PI HOCHMAN, SHAWN · 2000 to 2004
$1.7M
Closed-Loop Control of Spinal Motor Circuits using a Multi-electrode InterfaceR01EB006179 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI BELLAMKONDA, RAVI V. · 2007 to 2010
$1.3M
PROPERTIES OF THE MAMMALIAN SPINAL LOCOMOTOR NETWORKR01NS040440 · NINDS · EMORY UNIVERSITY · PI HOCHMAN, SHAWN · 2000 to 2003
$1.3M
DOPAMINERGIC CONTROL OF SPINAL CORD AND RESTLESS LEGSR01NS045248 · NINDS · EMORY UNIVERSITY · PI HOCHMAN, SHAWN · 2003 to 2006
$1.2M
NIBIB NIH HHS EB-006179NIBIB NIH HHS R01 EB006179NINDS NIH HHS NS-045248NINDS NIH HHS NS-40440NINDS NIH HHS NS-40893NINDS NIH HHS R01 NS040440NINDS NIH HHS R01 NS040893NINDS NIH HHS R01 NS045248
6 · The paper itself

Abstract

Recently, Andreas Husch, Nathan Cramer, and Ronald M. Harris-Warrick achieved a remarkable breakthrough in patch-clamp recordings of ventral horn neurons in the adult spinal cord slice preparation. This landmark study that breaks the "age barrier" is titled "Long-duration perforated patch recordings from spinal interneurons of adult mice" (Husch et al., in press). In it, the authors demonstrate the unprecedented ability to undertake day-long (up to 12 h), and utterly stable perforated patch recordings. A description of the methodology is detailed in their paper. Here, I give a brief overview before providing context to this extraordinary achievement.

Indexed as

AnimalsIn Vitro TechniquesLong-Term PotentiationNeuronsPatch-Clamp TechniquesSpinal Cord

Identifiers

PMID21957222
PMCPMC3234096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.