Evidence map›Paper›PMID 21957041›Full record

ReviewWiley interdisciplinary reviews. RNA

Eukaryotic 5S rRNA biogenesis.

Martin Ciganda, Noreen Williams

Abstract readReview
In one paragraph

Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed.

  1. Article
  2. Inherited human TFIIIA deficiency disrupts T cell development.medRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Small nucleolar RNAs: the hidden precursors of cancer ribosomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. International journal of molecular sciences · 2023
    Article
  18. Article
  19. Article
  20. Review

39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Martin CigandaDepartment of Microbiology and Immunology, University at Buffalo, Buffalo, NY, USA.
Noreen Williams

Funding

A novel preribosomal complex in trypanosomesR01GM092719 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WILLIAMS, NOREEN · 2010 to 2013
$1.3M
NIGMS NIH HHS R01 GM092719
6 · The paper itself

Abstract

The ribosome is a large complex containing both protein and RNA which must be assembled in a precise manner to allow proper functioning in the critical role of protein synthesis. 5S rRNA is the smallest of the RNA components of the ribosome, and although it has been studied for decades, we still do not have a clear understanding of its function within the complex ribosome machine. It is the only RNA species that binds ribosomal proteins prior to its assembly into the ribosome. Its transport into the nucleolus requires this interaction. Here we present an overview of some of the key findings concerning the structure and function of 5S rRNA and how its association with specific proteins impacts its localization and function.

Indexed as

AnimalsBase SequenceCytoplasmHumansMitochondriaModels, BiologicalModels, MolecularNucleic Acid ConformationRibosomal ProteinsRibosomesRNA-Binding ProteinsRNA Processing, Post-TranscriptionalRNA, Ribosomal, 5STranscription Factor TFIIIARibosomal ProteinsRNA-Binding ProteinsRNA, Ribosomal, 5STranscription Factor TFIIIA

Identifiers

PMID21957041
PMCPMC3278907

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.