ReviewWiley interdisciplinary reviews. RNA
Local translation of mRNAs in neural development.
Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 54 citations in OpenAlex.
- Article
- Development of perivascular astrocyte processes.Frontiers in neuroscience · 2025Review
- Axonal mRNA translation in neurological disorders.RNA biology · 2021Review
- Mitochondrial defects in the respiratory complex I contribute to impaired translational initiation via ROS and energy homeostasis in SMA motor neurons.Acta neuropathologica communications · 2020Article
- Growth and elongation of axons through mechanical tension mediated by fluorescent-magnetic bifunctional FeJournal of nanobiotechnology · 2020Article
- Fine-tuning the response of growth cones to guidance cues: a perspective on the role of microRNAs.Neural regeneration research · 2019Article
- A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons.Neuron · 2017Article
- Screening the Molecular Framework Underlying Local Dendritic mRNA Translation.Frontiers in molecular neuroscience · 2017Review
- RNA-binding profiles ofProceedings of the National Academy of Sciences of the United States of America · 2016Article
- The RNA-binding protein ATX-2 regulates cytokinesis through PAR-5 and ZEN-4.Molecular biology of the cell · 2016Article
- Adenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.Current drug targets · 2016Review
- Local protein synthesis in neuronal axons: why and how we study.BMB reports · 2015Review
- microRNAs in axon guidance.Frontiers in cellular neuroscience · 2014Review
- Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization.RNA (New York, N.Y.) · 2013Article
- Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics.Molecular and cellular biology · 2013Article
- Dendritic protein synthesis in the normal and diseased brain.Neuroscience · 2013Review
- Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Insights into the roles of local translation from the axonal transcriptome.Open biology · 2012Review
- Concentration-dependent requirement for local protein synthesis in motor neuron subtype-specific response to axon guidance cues.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Making and breaking synapses through local mRNA regulation.Current opinion in genetics & development · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Growing axons encounter numerous developmental signals to which they must promptly respond in order to properly form complex neural circuitry. In the axons, these signals are often transduced into a local increase or decrease in protein levels. Contrary to the traditional view that the cell bodies are the exclusive source of axonal proteins, it is becoming increasingly clear not only that de novo protein synthesis takes place in axons, but also that it is required for the axons to respond to certain signals. Here we review the current knowledge of local mRNA translation in developing neurons with a special focus on protein synthesis occurring in axons and growth cones.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.