Evidence map›Paper›PMID 21956888›Full record

ArticleAngewandte Chemie (International ed. in English)2011

Achieving secondary structural resolution in kinetic measurements of protein folding: a case study of the folding mechanism of Trp-cage.

Robert M Culik, Arnaldo L Serrano, Michelle R Bunagan, Feng Gai

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
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  6. ACS omega · 2020
    Article
  7. Article
  8. Article
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  14. Minimalist IR and fluorescence probes of protein function.Current opinion in chemical biology · 2016
    Review
  15. Article
  16. Review
  17. Article
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  19. Article
  20. How Sensitive is the Amide I Vibration of the Polypeptide Backbone to Electric Fields?Chemphyschem : a European journal of chemical physics and physical chemistry · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Robert M CulikDepartment of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Arnaldo L Serrano
Michelle R Bunagan
Feng Gai

Funding

ZN-INDUCED PEPTIDE FOLDINGP41RR001348 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI DEGRADO, WILLIAM · 1985 to 2011
$8.7M
STRUCTURAL BIOLOGY TRAINING PROGRAMT32GM008275 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI WAND, A. JOSHUA · 1988 to 2018
$6.0M
Spectroscopic Study of Protein Folding DynamicsR01GM065978 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI GAI, FENG · 2002 to 2014
$3.9M
Probing the Folding Mechanism of Intrinsically Disordered Proteins: The pKID/KIXF31AG039253 · NIA · UNIVERSITY OF PENNSYLVANIA · PI CULIK, ROBERT · 2011 to 2013
$126k
NCRR NIH HHS P41 RR001348NCRR NIH HHS RR01348NIA NIH HHS F31 AG039253NIGMS NIH HHS GM-008275NIGMS NIH HHS GM-065978NIGMS NIH HHS R01 GM065978NIGMS NIH HHS T32 GM008275
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SequenceCircular DichroismKineticsPeptidesProtein FoldingProtein Structure, SecondarySpectrophotometry, InfraredTransition TemperaturePeptidesTrp-cage peptide

Identifiers

PMID21956888
PMCPMC3331591

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.