Evidence map›Paper›PMID 21956167›Full record

ArticleAmerican journal of physiology. Cell physiology2011

Targeting therapeutic effects: subcellular location matters. Focus on "Pharmacological AMP-kinase activators have compartment-specific effects on cell physiology".

Judy Creighton

Abstract readEditorialComment
In one paragraph

Article in American journal of physiology. Cell physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. N-cadherin coordinates AMP kinase-mediated lung vascular repair.American journal of physiology. Lung cellular and molecular physiology · 2016
    Article
  2. Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury.American journal of physiology. Lung cellular and molecular physiology · 2013
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Judy Creighton

Funding

AMPK activates calcium signaling necessary for endothelial barrier repairR01HL102296 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CREIGHTON, JUDY · 2010 to 2014
$1.4M
NHLBI NIH HHS R01 HL102296
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adenylate KinaseCell NucleusCytoplasmEnzyme ActivatorsHumansAdenylate KinaseEnzyme Activators

Identifiers

PMID21956167
PMCPMC3233800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.