Evidence map›Paper›PMID 21955586›Full record

ArticleRNA biology

Animal snoRNAs and scaRNAs with exceptional structures.

Manja Marz, Andreas R Gruber, Christian Höner Zu Siederdissen, Fabian Amman, Stefan Badelt, Sebastian Bartschat, Stephan H Bernhart, Wolfgang Beyer, Stephanie Kehr, Ronny Lorenz and 5 more

Open access · hybridAbstract read
In one paragraph

Article in RNA biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. What is the Role of SNORA42 in Carcinogenesis? A Systematic Review.Asian Pacific journal of cancer prevention : APJCP · 2023
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. The medium-size noncoding RNA transcriptome ofNAR genomics and bioinformatics · 2020
    Article
  7. The Existence and Localization of Nuclear snoRNAs inPlants (Basel, Switzerland) · 2020
    Article
  8. Article
  9. Biology and clinical relevance of noncoding sno/scaRNAs.Trends in cardiovascular medicine · 2018
    Review
  10. Article
  11. Review
  12. Review
  13. An updated human snoRNAome.Nucleic acids research · 2016
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 6 countries.

Manja MarzRNA Bioinformatik Gruppe, Institut f¨ur Pharmazeutische Chemie, Philipps Universit¨at Marburg, Marburg, Germany.
Andreas R Gruber
Christian Höner Zu Siederdissen
Fabian Amman
Stefan Badelt
Sebastian Bartschat
Stephan H Bernhart
Wolfgang Beyer
Stephanie Kehr
Ronny Lorenz
Andrea Tanzer
Dilmurat Yusuf
Hakim Tafer
Ivo L Hofacker
Peter F Stadler
University of Vienna · ATTelstra (Australia) · AUBarcelona Biomedical Research Park · ESLund University · SEPhilipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overwhelming majority of small nucleolar RNAs (snoRNAs) fall into two clearly defined classes characterized by distinctive secondary structures and sequence motifs. A small group of diverse ncRNAs, however, shares the hallmarks of one or both classes of snoRNAs but differs substantially from the norm in some respects. Here, we compile the available information on these exceptional cases, conduct a thorough homology search throughout the available metazoan genomes, provide improved and expanded alignments, and investigate the evolutionary histories of these ncRNA families as well as their mutual relationships.

Indexed as

Nucleic Acid ConformationAnimalsBase SequenceCoiled BodiesGenomeHumansMolecular Sequence DataPhylogenyRNA, Small NucleolarSequence AlignmentSequence Homology, Nucleic AcidRNA, Small Nucleolar

Identifiers

PMID21955586
PMCPMC3256416
OpenAlexW2090301812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.