ArticleBMC microbiology2011
Evolution and diversity of community-associated methicillin-resistant Staphylococcus aureus in a geographical region.
Article in BMC microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- Whole-genome sequencing reveals a unique outbreak of methicillin-resistantInfection prevention in practice · 2026Article
- Culture-Based Wastewater Surveillance for the Detection and Monitoring of Antimicrobial Resistance in Staphylococcal Species.Veterinary sciences · 2025Article
- Genomic Epidemiology of Clonal Complex 1International journal of microbiology · 2025Article
- A prospective cohort study to investigate the transmission and burden ofMicrobial genomics · 2024Article
- Genomic characterization of a unique Panton-Valentine leucocidin-positive community-associated methicillin-resistantMicrobial genomics · 2023Article
- Clonal Complexes Distribution ofAntibiotics (Basel, Switzerland) · 2023Article
- Beyond CC398: Characterisation of Other Tetracycline and Methicillin-ResistantPathogens (Basel, Switzerland) · 2022Article
- Surveillance of osteoarticular infections caused byFrontiers in cellular and infection microbiology · 2022Article
- Resurgence of Chloramphenicol Resistance in Methicillin-ResistantAntibiotics (Basel, Switzerland) · 2021Article
- The Dissemination and Molecular Characterization of Clonal Complex 361 (CC361) Methicillin-ResistantFrontiers in microbiology · 2021Article
- Marked increase in community-associated methicillin-resistantEpidemiology and infection · 2020Article
- Diversity of bacteriophages encoding Panton-Valentine leukocidin in temporally and geographically related Staphylococcus aureus.PloS one · 2020Article
- Prevalence and predictors of MRSA carriage among employees in a non-outbreak setting: a cross-sectional study in an acute care hospital.Journal of occupational medicine and toxicology (London, England) · 2019Article
- In vitro and in vivo antimicrobial activity of TS2037, a novel aminoglycoside antibiotic.The Journal of antibiotics · 2018Article
- Distribution of staphylococcal cassette chromosomeIranian journal of microbiology · 2018Article
- Emerging variants of methicillin-resistant Staphylococcus aureus genotypes in Kuwait hospitals.PloS one · 2018Article
- Emerging multidrug-resistant Bengal Bay clone ST772-MRSA-V in Norway: molecular epidemiology 2004-2014.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Emergence and spread of a new community-genotype methicillin-resistant Staphylococcus aureus clone in Colombia.BMC infectious diseases · 2017Article
- Dominance of community-associated methicillin-resistant Staphylococcus aureus clones in a maternity hospital.PloS one · 2017Article
- Molecular Epidemiology of Methicillin-Resistant Staphylococcus aureus Isolated from Australian Veterinarians.PloS one · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCommunity-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was first reported in remote regions of Western Australia and is now the predominant MRSA isolated in the state. The objective of this study is to determine the genetic relatedness of Western Australian CA-MRSA clones within different multilocus sequence type (MLST) clonal clusters providing an insight into the frequency of S. aureus SCCmec acquisition within a region.
resultsThe CA-MRSA population in Western Australia is genetically diverse consisting of 83 unique pulsed-field gel electrophoresis strains from which 46 MLSTs have been characterised. Forty five of these sequence types are from 18 MLST clonal clusters and two singletons. While SCCmec IV and V are the predominant SCCmec elements, SCCmec VIII and several novel and composite SCCmec elements are present. The emergence of MRSA in diverse S. aureus clonal clusters suggests horizontal transmission of the SCCmec element has occurred on multiple occasions. Furthermore DNA microarray and spa typing suggests horizontal transfer of SCCmec elements has also occurred within the same CC. For many single and double locus variant CA-MRSA clones only a few isolates have been detected.
conclusionsAlthough multiple CA-MRSA clones have evolved in the Western Australian community only three clones have successfully adapted to the Western Australian community environment. These data suggest the successful evolution of a CA-MRSA clone may not only depend on the mobility of the SCCmec element but also on other genetic determinants.
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