ArticleThe Journal of organic chemistry2011
Synthesis and structural verification of the xylomannan antifreeze substance from the freeze-tolerant Alaskan beetle Upis ceramboides.
Article in The Journal of organic chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 18 citations in OpenAlex.
- Chemical synthesis-based structure correction of a claimed protein-free antifreeze oligosaccharide.National science review · 2024Article
- Expeditious chemical synthesis of xylomannans disproves the proposed antifreeze activities.National science review · 2024Article
- En Route to the Transformation of Glycoscience: A Chemist's Perspective on Internal and External Crossroads in Glycochemistry.Journal of the American Chemical Society · 2021Article
- Synthesis and O-Glycosidic Linkage Conformational Analysis ofThe Journal of organic chemistry · 2019Article
- Synthesis of LewisCarbohydrate research · 2017Article
- From ice-binding proteins to bio-inspired antifreeze materials.Soft matter · 2017Review
- Automated fluorous-assisted solution-phase synthesis of β-1,2-, 1,3-, and 1,6-mannan oligomers.Carbohydrate research · 2016Article
- Automated Solution-Phase Synthesis of β-1,4-Mannuronate and β-1,4-Mannan.Organic letters · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Tetra-, hexa-, and octasaccharide subunits of the [→4)-β-D-Manp-(1→4)-β-D-Xylp-(1→](n) xylomannan motif proposed as the structure of a novel nonprotein, thermal hysteresis-producing antifreeze substance from the freeze-tolerant Alaskan beetle Upis ceramboides have been accessed by total chemical synthesis. Comparison of their NMR spectral data with data of the isolate lends strong support to the proposed structure. Synthetic tetrasaccharides representing various linkage isomers considered (α- rather than β-manno, and linkage through mannose O3 rather than O4) show more significant chemical shift differences with the isolate and are therefore excluded from further consideration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.