ArticleNanomedicine (London, England)2011
Emerging technologies in medical applications of minimum volume vitrification.
Article in Nanomedicine (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Research Progress on Mammalian Oocyte Vitrification: From Damage Mechanisms to Optimization Strategies.Animals : an open access journal from MDPI · 2026Review
- Nanotechnology-Driven Precision Modulation of Transplant Immunity: From Mechanistic Insights to Clinical Tolerance.International journal of nanomedicine · 2026Review
- Automated Manufacturing Processes and Platforms for Large-scale Production of Clinical-grade Mesenchymal Stem/ Stromal Cells.Stem cell reviews and reports · 2025Review
- De novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation.Journal of nanobiotechnology · 2024Review
- Testicular Tissue Vitrification: a Promising Strategy for Male Fertility Preservation.Reproductive sciences (Thousand Oaks, Calif.) · 2023Review
- Handling, Reproducing and Cryopreserving Five European Sea Urchins (Echinodermata, Klein, 1778) for Biodiversity Conservation Purposes.Animals : an open access journal from MDPI · 2022Article
- Long-term and short-term preservation strategies for tissue engineering and regenerative medicine products: state of the art and emerging trends.PNAS nexus · 2022Review
- Cryopreservation of Tissue-Engineered Scaffold-Based Constructs: from Concept to Reality.Stem cell reviews and reports · 2022Review
- Developmental Plasticity in Response to Embryo Cryopreservation: The Importance of the Vitrification Device in Rabbits.Animals : an open access journal from MDPI · 2020Article
- [Experimental study on high throughput vitrification by micro-droplet spray method].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019Article
- A non-traditional approach to cryopreservation by ultra-rapid cooling for human mesenchymal stem cells.PloS one · 2019Article
- The Unusual Properties of Polytetrafluoroethylene Enable Massive-Volume Vitrification of Stem Cells with Low-Concentration Cryoprotectants.Advanced materials technologies · 2019Article
- Article
- Bio-inspired solute enables preservation of human oocytes using minimum volume vitrification.Journal of tissue engineering and regenerative medicine · 2018Article
- Hydrogel Encapsulation Facilitates Rapid-Cooling Cryopreservation of Stem Cell-Laden Core-Shell Microcapsules as Cell-Biomaterial Constructs.Advanced healthcare materials · 2017Article
- Development of Synthetic and Natural Materials for Tissue Engineering Applications Using Adipose Stem Cells.Stem cells international · 2016Review
- High-Throughput Non-Contact Vitrification of Cell-Laden Droplets Based on Cell Printing.Scientific reports · 2015Article
- Phenotypic and functional characterization of long-term cryopreserved human adipose-derived stem cells.Scientific reports · 2015Article
- Preserving human cells for regenerative, reproductive, and transfusion medicine.Biotechnology journal · 2014Review
- Exhaustion of racing sperm in nature-mimicking microfluidic channels during sorting.Small (Weinheim an der Bergstrasse, Germany) · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Cell/tissue biopreservation has broad public health and socio-economic impact affecting millions of lives. Cryopreservation technologies provide an efficient way to preserve cells and tissues targeting the clinic for applications including reproductive medicine and organ transplantation. Among these technologies, vitrification has displayed significant improvement in post-thaw cell viability and function by eliminating harmful effects of ice crystal formation compared to the traditional slow freezing methods. However, high cryoprotectant agent concentrations are required, which induces toxicity and osmotic stress to cells and tissues. It has been shown that vitrification using small sample volumes (i.e., <1 µl) significantly increases cooling rates and hence reduces the required cryoprotectant agent levels. Recently, emerging nano- and micro-scale technologies have shown potential to manipulate picoliter to nanoliter sample sizes. Therefore, the synergistic integration of nanoscale technologies with cryogenics has the potential to improve biopreservation methods.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.