ArticleWorld journal of diabetes2011
Developmental programming of the metabolic syndrome - critical windows for intervention.
Article in World journal of diabetes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
27 citing papers in PubMed.
- The Motor Neuromuscular Axis: The Overlooked Element of Developmental Programming in Diabetes and Metabolic Syndrome.International journal of molecular sciences · 2026Review
- Maternal Lecithin Supplementation in Sows Regulates the Hepatic Glycolipid Metabolism of Offspring.Animals : an open access journal from MDPI · 2025Article
- Impact of Neonatal Activation of Nuclear Receptor CAR (Nr1i3) on Cyp2 Gene Expression in Adult Mouse Liver.Toxicological sciences : an official journal of the Society of Toxicology · 2022Article
- Maternal low protein diet and fetal programming of lean type 2 diabetes.World journal of diabetes · 2022Review
- The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats.Physiological reports · 2019Article
- Short-Term Neonatal Oral Administration of Oleanolic Acid Protects against Fructose-Induced Oxidative Stress in the Skeletal Muscles of Suckling Rats.Molecules (Basel, Switzerland) · 2019Article
- Prenatal Malnutrition-Induced Epigenetic Dysregulation as a Risk Factor for Type 2 Diabetes.International journal of genomics · 2019Review
- Phenotypic Switching Resulting From Developmental Plasticity: Fixed or Reversible?Frontiers in physiology · 2019Review
- Gestational Hyperandrogenism in Developmental Programming.Endocrinology · 2017Review
- Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats.Scientific reports · 2016Article
- Realizing the Potential of Adolescence to Prevent Transgenerational Conditioning of Noncommunicable Disease Risk: Multi-Sectoral Design Frameworks.Healthcare (Basel, Switzerland) · 2016Review
- Maternal high-fat feeding leads to alterations of brain glucose metabolism in the offspring: positron emission tomography study in a porcine model.Diabetologia · 2016Article
- Challenges and opportunities in developmental integrative physiology.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2015Review
- Childhood overweight and obesity in a region of Italian immigration in Southern Brazil: a cross-sectional study.Italian journal of pediatrics · 2015Article
- Overweight and obesity in children with congenital heart disease: combination of risks for the future?BMC pediatrics · 2014Article
- High fat and/or high salt intake during pregnancy alters maternal meta-inflammation and offspring growth and metabolic profiles.Physiological reports · 2014Article
- Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Sex-specific effects of exercise ancestry on metabolic, morphological and gene expression phenotypes in multiple generations of mouse offspring.Experimental physiology · 2013Article
- Influence of early-life nutrition on mortality and reproductive success during a subsequent famine in a preindustrial population.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Early life programming and metabolic syndrome.World journal of pediatrics : WJP · 2013Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic disease results from a complex interaction of many factors, including genetic, physiological, behavioral and environmental influences. The recent rate at which these diseases have increased suggests that environmental and behavioral influences, rather than genetic causes, are fuelling the present epidemic. In this context, the developmental origins of health and disease hypothesis has highlighted the link between the periconceptual, fetal and early infant phases of life and the subsequent development of adult obesity and the metabolic syndrome. Although the mechanisms are yet to be fully elucidated, this programming was generally considered an irreversible change in developmental trajectory. Recent work in animal models suggests that developmental programming of metabolic disorders is potentially reversible by nutritional or targeted therapeutic interventions during the period of developmental plasticity. This review will discuss critical windows of developmental plasticity and possible avenues to ameliorate the development of postnatal metabolic disorders following an adverse early life environment.
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Registered trials
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