Evidence map›Paper›PMID 21954346›Full record

ReviewInternational journal of molecular sciences2011

Identification and Role of Regulatory Non-Coding RNAs in

Benjamin Izar, Mobarak Abu Mraheil, Torsten Hain

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Bacterial Small RNAs in the GenusInternational journal of molecular sciences · 2018
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Current status of antisense RNA-mediated gene regulation in Listeria monocytogenes.Frontiers in cellular and infection microbiology · 2014
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Benjamin IzarInstitute of Medical Microbiology, Justus-Liebig-University, Frankfurter Strasse 107, Giessen 35392, Germany; E-Mails: Benjamin.Izar@med.uni-giessen.de (B.I.); Mobarak.Mraheil@mikrobio.med.uni-giessen.de (M.A.M.).
Mobarak Abu Mraheil
Torsten Hain
University of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial regulatory non-coding RNAs control numerous mRNA targets that direct a plethora of biological processes, such as the adaption to environmental changes, growth and virulence. Recently developed high-throughput techniques, such as genomic tiling arrays and RNA-Seq have allowed investigating prokaryotic cis- and trans-acting regulatory RNAs, including sRNAs, asRNAs, untranslated regions (UTR) and riboswitches. As a result, we obtained a more comprehensive view on the complexity and plasticity of the prokaryotic genome biology. Listeria monocytogenes was utilized as a model system for intracellular pathogenic bacteria in several studies, which revealed the presence of about 180 regulatory RNAs in the listerial genome. A regulatory role of non-coding RNAs in survival, virulence and adaptation mechanisms of L. monocytogenes was confirmed in subsequent experiments, thus, providing insight into a multifaceted modulatory function of RNA/mRNA interference. In this review, we discuss the identification of regulatory RNAs by high-throughput techniques and in their functional role in L. monocytogenes.

Indexed as

Gene Expression Regulation, Bacterial5' Untranslated RegionsHigh-Throughput Screening AssaysHost Factor 1 ProteinListeria monocytogenesRegulatory Sequences, Ribonucleic AcidRNA, AntisenseRNA, BacterialRNA InterferenceRNA, MessengerRNA, Small UntranslatedRNA, Untranslated5' Untranslated RegionsHost Factor 1 ProteinRegulatory Sequences, Ribonucleic AcidRNA, AntisenseRNA, BacterialRNA, MessengerRNA, Small UntranslatedRNA, UntranslatedasRNAinfectionListeria monocytogenesnon-coding RNAregulatory RNAriboswitchRNA-SeqsRNAUTRwhole genome tiling arrays

Identifiers

PMID21954346
PMCPMC3179153
OpenAlexW2061154887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.