ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2011
Tissue interaction is required for glenoid fossa development during temporomandibular joint formation.
Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 48 citations in OpenAlex.
- Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease.Journal of anatomy · 2026Article
- The capsular vein as a novel surgical landmark for safe access to the temporomandibular joint: a retrospective cohort study.Maxillofacial plastic and reconstructive surgery · 2025Article
- Comparison of knee joint and temporomandibular joint development in pig embryos.Animal biotechnology · 2024Article
- Evolution and development of the mammalian jaw joint: Making a novel structure.Evolution & development · 2023Review
- Quantitative bone imaging biomarkers and joint space analysis of the articular Fossa in temporomandibular joint osteoarthritis using artificial intelligence models.Frontiers in dental medicine · 2022Article
- Evidence of vasculature and chondrocyte to osteoblast transdifferentiation in craniofacial synovial joints: Implications for osteoarthritis diagnosis and therapy.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- The TMJ Disc Is a Common Ancestral Feature in All Mammals, as Evidenced by the Presence of a Rudimentary Disc During Monotreme Development.Frontiers in cell and developmental biology · 2020Article
- The Roles of Indian Hedgehog Signaling in TMJ Formation.International journal of molecular sciences · 2019Review
- Persistent Wnt/β-catenin signaling in mouse epithelium induces the ectopicOrganogenesis · 2019Article
- Vital Roles of β-catenin in Trans-differentiation of Chondrocytes to Bone Cells.International journal of biological sciences · 2018Article
- Major evolutionary transitions and innovations: the tympanic middle ear.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Review
- Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice.Molecular medicine reports · 2016Article
- A Joint Less Ordinary: Intriguing Roles for Hedgehog Signalling in the Development of the Temporomandibular Synovial Joint.Journal of developmental biology · 2016Review
- Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice.Cell and tissue research · 2016Article
- Observing the development of the temporomandibular joint in embryonic and post-natal mice using various staining methods.Experimental and therapeutic medicine · 2016Article
- Mouse genetic models for temporomandibular joint development and disorders.Oral diseases · 2016Review
- Overexpression of Indian hedgehog partially rescues short stature homeobox 2-overexpression-associated congenital dysplasia of the temporomandibular joint in mice.Molecular medicine reports · 2015Article
- Species-specific modifications of mandible shape reveal independent mechanisms for growth and initiation of the coronoid.EvoDevo · 2015Article
- Overexpression of Shox2 leads to congenital dysplasia of the temporomandibular joint in mice.International journal of molecular sciences · 2014Article
- BMPRIA mediated signaling is essential for temporomandibular joint development in mice.PloS one · 2014Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 2 countries.
Funding
Abstract
The mammalian temporomandibular joint (TMJ) develops from two distinct mesenchymal condensations that grow toward each other and ossify through different mechanisms, with the glenoid fossa undergoing intramembranous ossification while the condyle being endochondral in origin. In this study, we used various genetically modified mouse models to investigate tissue interaction between the condyle and glenoid fossa during TMJ formation in mice. We report that either absence or dislocation of the condyle results in an arrested glenoid fossa development. In both cases, glenoid fossa development was initiated, but failed to sustain, and became regressed subsequently. However, condyle development appears to be independent upon the presence of the forming glenoid fossa. In addition, we show that substitution of condyle by Meckel's cartilage is able to sustain glenoid fossa development. These observations suggest that proper signals from the developing condyle or Meckel's cartilage are required to sustain the glenoid fossa development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.