Evidence map›Paper›PMID 21953433›Full record

ArticleDevelopmental psychobiology2012

Eyeblink conditioning in the developing rabbit.

Kevin L Brown, Diana S Woodruff-Pak

Abstract read
In one paragraph

Article in Developmental psychobiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kevin L BrownDepartment of Psychology, Temple University, Philadelphia, PA 19122, USA.
Diana S Woodruff-Pak
Temple University · US

Funding

Mechanisms of Associative Learning in Aging: Mouse ModelsR01AG023742 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI WOODRUFF-PAK, DIANA S · 2006 to 2010
$1.9M
Aging and Sties of Action of Cognition-Enhancing DrugsR01AG021925 · NIA · TEMPLE UNIV OF THE COMMONWEALTH · PI WOODRUFF-PAK, DIANA S · 2004 to 2008
$1.4M
NIA NIH HHS 1 R01 AG021925NIA NIH HHS 1 R01 AG023742NIA NIH HHS R01 AG021925NIA NIH HHS R01 AG023742
6 · The paper itself

Abstract

Eyeblink classical conditioning in pre-weanling rabbits was examined in the present study. Using a custom lightweight headpiece and restrainer, New Zealand white littermates were trained once daily in 400 ms delay eyeblink classical conditioning from postnatal days (PD) 17-21 or PD 24-28. These ages were chosen because eyeblink conditioning emerges gradually over PD 17-24 in rats [Stanton et al., (1992) Behavioral Neuroscience, 106(4):657-665], another altricial species with neurodevelopmental features similar to those of rabbits. Consistent with well-established findings in rats, rabbits trained from PD 24-28 showed greater conditioning relative to littermates trained from PD 17-21. Both age groups displayed poor retention of eyeblink conditioning at retraining 1 month after acquisition. These findings are the first to demonstrate eyeblink conditioning in the developing rabbit. With further characterization of optimal conditioning parameters, this preparation may have applications to neurodevelopmental disease models as well as research exploring the ontogeny of memory.

Indexed as

AnimalsAnimals, NewbornConditioning, ClassicalConditioning, EyelidFemaleMaleRabbits

Identifiers

PMID21953433
PMCPMC3251633
OpenAlexW2100729398

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.