Evidence map›Paper›PMID 21953336›Full record

GuidelineAnnals of the rheumatic diseases2012

European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies.

L Gossec, J S Smolen, C Gaujoux-Viala, Z Ash, H Marzo-Ortega, D van der Heijde, O FitzGerald, D Aletaha, P Balint, D Boumpas and 26 more

Open access · bronzeAbstract readConsensus StatementPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Annals of the rheumatic diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 130 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 11 pooled it
38.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 11 syntheses or guidelines pooled it, 447 citations in OpenAlex.

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  3. French guidelines on the use of systemic treatments for moderate-to-severe psoriasis in adults.Journal of the European Academy of Dermatology and Venereology : JEADV · 2019
    Guideline
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70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 15 countries.

L GossecParis Descartes University, Paris, France. laure.gossec@cch.aphp.fr
J S Smolen
C Gaujoux-Viala
Z Ash
H Marzo-Ortega
D van der Heijde
O FitzGerald
D Aletaha
P Balint
D Boumpas
J Braun
F C Breedveld
G Burmester
J D Cañete
M de Wit
H Dagfinrud
K de Vlam
M Dougados
P Helliwell
A Kavanaugh
T K Kvien
R Landewé
T Luger
M Maccarone
D McGonagle
N McHugh
I B McInnes
C Ritchlin
J Sieper
P P Tak
G Valesini
J Vencovsky
K L Winthrop
A Zink
P Emery
European League Against Rheumatism
University of Leeds · GBCharité - Universitätsmedizin Berlin · DEDélégation Paris 5 · FRLeiden University Medical Center · NLMedical University of Vienna · ATNIHR Leeds Musculoskeletal Biomedical Research Unit · GBAcademic Medical Center · NLConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESDiakonhjemmet Hospital · NOEuropean League Against Rheumatism · CHGerman Rheumatism Research Centre · DEInstitute of Rheumatology · CZKU Leuven · BEMaastricht University Medical Centre · NLNational Institute of Oncology · HUOregon Health & Science University · USRoyal National Hospital for Rheumatic Diseases · GBRuhr University Bochum · DESapienza University of Rome · ITSorbonne Université · FR

Funding

Versus Arthritis 18475
6 · The paper itself

Abstract

backgroundPsoriatic arthritis (PsA) is a clinically heterogeneous disease. Clear consensual treatment guidance focused on the musculoskeletal manifestations of PsA would be advantageous. The authors present European League Against Rheumatism (EULAR) recommendations for the treatment of PsA with systemic or local (non-topical) symptomatic and disease-modifying antirheumatic drugs (DMARD).

methodsThe recommendations are based on evidence from systematic literature reviews performed for non-steroidal anti-inflammatory drugs (NSAID), glucocorticoids, synthetic DMARD and biological DMARD. This evidence was discussed, summarised and recommendations were formulated by a task force comprising 35 representatives, and providing levels of evidence, strength of recommendations and levels of agreement.

resultsTen recommendations were developed for treatment from NSAID through synthetic DMARD to biological agents, accounting for articular and extra-articular manifestations of PsA. Five overarching principles and a research agenda were defined.

conclusionThese recommendations are intended to provide rheumatologists, patients and other stakeholders with a consensus on the pharmacological treatment of PsA and strategies to reach optimal outcomes, based on combining evidence and expert opinion. The research agenda informs directions within EULAR and other communities interested in PsA.

Indexed as

Antirheumatic AgentsArthritis, PsoriaticComorbidityEuropeEvidence-Based MedicineGlucocorticoidsHumansInternational CooperationTumor Necrosis Factor-alphaAntirheumatic AgentsGlucocorticoidsTumor Necrosis Factor-alpha

Identifiers

PMID21953336
OpenAlexW2171122996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.