ArticleBritish journal of cancer2011
Antibodies against lytic and latent Kaposi's sarcoma-associated herpes virus antigens and lymphoma in the European EpiLymph case-control study.
Article in British journal of cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Oral Shedding of an Oncogenic Virus Alters the Oral Microbiome in HIV+ Patients.Frontiers in microbiology · 2022Article
- Splenic marginal zone B-cell lymphoma associated with ruptured breast implants: case report and review of the literature.Case reports in plastic surgery & hand surgery · 2021Article
- Porphyromonas gingivalis coinfects with KSHV in oral cavities of HIV+ patients and induces viral lytic reactivation.Journal of medical virology · 2020Article
- Kaposi Sarcoma-Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation.The Journal of infectious diseases · 2020Article
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- Kaposi sarcoma.Nature reviews. Disease primers · 2019Review
- Transactivation of human endogenous retrovirus K (HERV-K) by KSHV promotes Kaposi's sarcoma development.Oncogene · 2018Article
- Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma.Blood · 2015Article
- Induction of hyaluronan production by oncogenic KSHV and the contribution to viral pathogenesis in AIDS patients.Cancer letters · 2015Article
- The product of Kaposi's sarcoma-associated herpesvirus immediate early gene K4.2 regulates immunoglobulin secretion and calcium homeostasis by interacting with and inhibiting pERP1.Journal of virology · 2013Article
- Kaposi sarcoma associated herpesvirus pathogenesis (KSHV)--an update.Current opinion in virology · 2013Review
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Authors and funding
14 authors at 11 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundKaposi's sarcoma-associated herpes virus is associated with primary effusion lymphoma and multicentric Castleman's disease.
methodsSeropositivity to lytic and latent Kaposi's sarcoma herpes virus (KSHV) antigens were examined in 2083 lymphomas and 2013 controls from six European countries.
resultsAntibodies against KSHV latent and lytic antigens were detectable in 4.5% and 3.4% of controls, respectively, and 3.6% of cases (P>0.05). The KSHV seropositivity was associated with splenic marginal zone lymphoma (SMZL) (odds ratio (OR)=4.11, 95% confidence interval (CI)=1.57-10.83) and multiple myeloma (OR=0.31, 95% CI=0.11-0.85).
conclusionThe KSHV is unlikely to contribute importantly to lymphomagenesis among immunocompetent subjects. However, the observed association with SMZL may underline a chronic antigen mechanism in its aetiology.
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