Evidence map›Paper›PMID 21952221›Full record

ReviewNature communications2011

Capturing the essence of folding and functions of biomolecules using coarse-grained models.

Changbong Hyeon, D Thirumalai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Molecular Crowding by Computational Approaches.Sub-cellular biochemistry · 2025
    Review
  5. Understanding and Simulating the Dynamics of a Polymer-Like Chromatin.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. A TeZla micromixer for interrogating the early and broad folding landscape of G-quadruplex via multistage velocity descending.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Contrastive Learning of Coarse-Grained Force Fields.Journal of chemical theory and computation · 2022
    Article
  16. Article
  17. Polymer Modeling of 3D Epigenome Folding: Application to Drosophila.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  18. Article
  19. Article
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Changbong HyeonSchool of Computational Sciences, Korea Institute for Advanced Study, Seoul 130-722, Republic of Korea.
D Thirumalai

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example, during chromosome organization. Describing phenomena that cover such diverse length, and also time, scales requires models that capture the underlying physics for the particular length scale of interest. Theoretical ideas, in particular, concepts from polymer physics, have guided the development of coarse-grained models to study folding of DNA, RNA and proteins. More recently, such models and their variants have been applied to the functions of biological nanomachines. Simulations using coarse-grained models are now poised to address a wide range of problems in biology.

Indexed as

Models, MolecularProtein FoldingDNARNADNARNA

Identifiers

PMID21952221

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.