ArticleBMC plant biology2011
Role of TRIPTYCHON in trichome patterning in Arabidopsis.
Article in BMC plant biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Multi-omics insights into the woolly trait of Saussurea medusa and the plant's coordinated regulation of flavonoid biosynthesis.Communications biology · 2026Article
- Gene-centered identification of cis-regulatory islands highlights regulatory landscapes complementary to motif-centric approaches.BMC genomics · 2026Article
- Multifaceted Roles of SPL9 in Plant Growth, Development, and Stress Responses: A Review.Plants (Basel, Switzerland) · 2026Review
- Identification of bZIP Transcription Factors That Regulate the Development of Leaf Epidermal Cells inInternational journal of molecular sciences · 2024Article
- A 3D gene expression atlas of the floral meristem based on spatial reconstruction of single nucleus RNA sequencing data.Nature communications · 2022Article
- The Genetic Complexity of Type-IV Trichome Development Reveals the Steps towards an Insect-Resistant Tomato.Plants (Basel, Switzerland) · 2022Article
- Comparative expression analysis in three Brassicaceae species revealed compensatory changes of the underlying gene regulatory network.Frontiers in plant science · 2022Article
- Comparative Transcriptome Analysis of Hard and Tender Fruit Spines of Cucumber to Identify Genes Involved in the Morphological Development of Fruit Spines.Frontiers in plant science · 2022Article
- Identification and characterization of PaGL1-like genes from Platanus acerifolia related to the regulation of trichomes.Plant molecular biology · 2020Article
- GaHD1, a candidate gene for the Gossypium arboreum SMA-4 mutant, promotes trichome and fiber initiation by cellular HPlant molecular biology · 2020Article
- Modulating Protein Stability to Switch Toxic Protein Function On and Off in Living Cells.Plant physiology · 2019Article
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- Sub-epidermal Expression ofFrontiers in plant science · 2018Article
- Mapping of genetic locus for leaf trichome in Brassica oleracea.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- TRANSPARENT TESTA GLABRA1 and GLABRA1 Compete for Binding to GLABRA3 in Arabidopsis.Plant physiology · 2015Article
- Arabidopsis TTG2 regulates TRY expression through enhancement of activator complex-triggered activation.The Plant cell · 2014Article
- Transcriptome profiling reveals roles of meristem regulators and polarity genes during fruit trichome development in cucumber (Cucumis sativus L.).Journal of experimental botany · 2014Article
- Leaf development: a cellular perspective.Frontiers in plant science · 2014Review
- Comparison of five major trichome regulatory genes in Brassica villosa with orthologues within the Brassicaceae.PloS one · 2014Article
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2 authors.
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Abstract
backgroundTrichome patterning in Arabidopsis thaliana is governed by three types of activators, R2R3MYB, bHLH and WD40 proteins, and six R3MYB inhibitors. Among the inhibitors TRIPTYCHON (TRY) seems to fulfill a special function. Its corresponding mutants produce trichome clusters whereas all other inhibitors are involved in trichome density regulation.
resultsTo better understand the role of TRY in trichome patterning we analyzed its transcriptional regulation. A promoter analysis identified the relevant regulatory region for trichome patterning. This essential region contains a fragment required for a double negative feedback loop such that it mediates the repression of TRY/CPC auto-repression. By transforming single cells of pTRY:GUS lines with p35S:GL1, p35S:GL3 and p35S:TTG1 in the presence or absence of p35S:TRY or p35S:CPC we demonstrate that TRY and CPC can suppress the TRY expression without the transcriptional down regulation of the activators. We further show by promoter/CDS swapping experiments for the R3MYB inhibitors TRY and CPC that the TRY protein has specific properties relevant in the context of both, cluster formation and trichome density.
conclusionsOur identification of a TRY promoter fragment mediating a double negative feedback loop reveals new insight in the regulatory network of the trichome patterning machinery. In addition we show that the auto-repression by TRY can occur without a transcriptional down regulation of the activators, suggesting that the differential complex formation model has a biological significance. Finally we show that the unique role of TRY among the inhibitors is a property of the TRY protein.
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