Evidence map›Paper›PMID 21951526›Full record

ArticleMethods in cell biology2011

In vivo analysis of white adipose tissue in zebrafish.

James E N Minchin, John F Rawls

Open access · greenAbstract read
In one paragraph

Article in Methods in cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
10.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  11. Review
  12. A novel gnotobiotic experimental system for Atlantic salmon (Frontiers in cellular and infection microbiology · 2022
    Article
  13. Article
  14. Toward QuantitativeFrontiers in cell and developmental biology · 2021
    Article
  15. Wild-Type Zebrafish (Animals : an open access journal from MDPI · 2020
    Review
  16. Article
  17. Article
  18. Article
  19. Obese zebrafish: A small fish for a major human health condition.Animal models and experimental medicine · 2018
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

James E N MinchinDepartment of Cell and Molecular Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
John F Rawls
University of North Carolina at Chapel Hill · US

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
Microbial Regulation of Host Nutrient MetabolismR01DK081426 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RAWLS, JOHN F · 2008 to 2019
$3.9M
Microbial regulation of host nutrient metabolism in gnotobiotic zebrafishK01DK073695 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RAWLS, JOHN F · 2006 to 2009
$510k
NIDDK NIH HHS DK056350NIDDK NIH HHS DK073695NIDDK NIH HHS DK081426NIDDK NIH HHS K01 DK073695NIDDK NIH HHS P30 DK056350NIDDK NIH HHS R01 DK081426
6 · The paper itself

Abstract

White adipose tissue (WAT) is the major site of energy storage in bony vertebrates, and also serves central roles in the endocrine regulation of energy balance. The cellular and molecular mechanisms underlying WAT development and physiology are not well understood. This is due in part to difficulties associated with imaging adipose tissues in mammalian model systems, especially during early life stages. The zebrafish (Danio rerio) has recently emerged as a new model system for adipose tissue research, in which WAT can be imaged in a transparent living vertebrate at all life stages. Here we present detailed methods for labeling adipocytes in live zebrafish using fluorescent lipophilic dyes, and for in vivo microscopy of zebrafish WAT.

Indexed as

AdipogenesisAdipocytesAdipose Tissue, WhiteAnimalsDevelopmental BiologyEmbryo, NonmammalianEnergy MetabolismFemaleFixativesFluorescent DyesLarvaLipidsMaleMicroscopy, FluorescenceMolecular ImagingStaining and LabelingFixativesFluorescent DyesLipids

Identifiers

PMID21951526
PMCPMC4846293
OpenAlexW1532811277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.