ArticleAnnals of the New York Academy of Sciences2011
Sources of calretinin inputs to motoneurons of extraocular muscles involved in upgaze.
Article in Annals of the New York Academy of Sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Cross-species lesion mapping links a midbrain circuit to vergence dysfunction.Brain : a journal of neurology · 2026Article
- Macaque monkey trigeminal blink reflex circuits targeting levator palpebrae superioris motoneurons.The Journal of comparative neurology · 2021Article
- Histochemical Characterization of the Vestibular Y-Group in Monkey.Cerebellum (London, England) · 2021Article
- Transmitter and ion channel profiles of neurons in the primate abducens and trochlear nuclei.Brain structure & function · 2021Article
- Superior colliculus projections to target populations in the supraoculomotor area of the macaque monkey.Visual neuroscience · 2021Article
- A Subset of Palisade Endings Only in the Medial and Inferior Rectus Muscle in Monkey Contain Calretinin.Investigative ophthalmology & visual science · 2018Article
- Identification of Functional Cell Groups in the Abducens Nucleus of Monkey and Human by Perineuronal Nets and Choline Acetyltransferase Immunolabeling.Frontiers in neuroanatomy · 2018Article
- Identification of secondary vestibulo-ocular neurons in human based on their histochemical characteristics found in monkey.Journal of neurology · 2017Article
- Functional morphometry demonstrates extraocular muscle compartmental contraction during vertical gaze changes.Journal of neurophysiology · 2016Article
- Calretinin as a Marker for Premotor Neurons Involved in Upgaze in Human Brainstem.Frontiers in neuroanatomy · 2015Article
- Transmitter inputs to different motoneuron subgroups in the oculomotor and trochlear nucleus in monkey.Frontiers in neuroanatomy · 2015Article
- Modulation of the input-output function by GABAA receptor-mediated currents in rat oculomotor nucleus motoneurons.The Journal of physiology · 2014Article
- Delineation of motoneuron subgroups supplying individual eye muscles in the human oculomotor nucleus.Frontiers in neuroanatomy · 2014Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Recent monkey studies showed that motoneurons of the oculomotor nucleus involved in upward eye movements receive a selective input from afferents containing calretinin (CR). Here, we investigated the sources of these CR-positive afferents. After injections of tract-tracers into the oculomotor nucleus (nIII) of two monkeys, the retrograde labeling was combined with CR-immunofluorescence in frozen brainstem sections. Three sources of CR inputs to nIII were found: the rostral interstitial nucleus of the medial longitudinal fascicle (RIMLF), the interstitial nucleus of Cajal, and the y-group. CR is not present in all premotor upward-moving pathways. The excitatory secondary vestibulo-ocular neurons in the magnocellular part of the medial vestibular nuclei contained nonphosphorylated neurofilaments, but no CR, and they received a strong supply of large CR-positive boutons. In conclusion, the present study presents evidence that only specific premotor pathways for upward eye movements--excitatory upgaze pathways--contain CR, but not the up vestibulo-ocular reflex pathways. This property may help to differentiate between premotor up- and downgaze pathways in correlative clinico-anatomical studies in humans.
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