ArticleNeurology research international2012
Multimodal MRI neuroimaging biomarkers for cognitive normal adults, amnestic mild cognitive impairment, and Alzheimer's disease.
Article in Neurology research international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Obstructive sleep apnea and attention deficits: A systematic review of magnetic resonance imaging biomarkers and neuropsychological assessments.Brain and behavior · 2023Pooled it
- From Structure to Function and Back Again: A GAN-Guided Diffusion Framework for Generating Clinically Meaningful Multimodal Neuroimaging Data.Research square · 2026Article
- Structural and functional differences in the brains of patients with MCI with and without depressive symptoms and their relations with Alzheimer's disease: an MRI study.Psychoradiology · 2023Article
- Mouse brain MR super-resolution using a deep learning network trained with optical imaging data.Frontiers in radiology · 2023Article
- Distinctive Alterations of Functional Connectivity Strength between Vascular and Amnestic Mild Cognitive Impairment.Neural plasticity · 2021Article
- Traditional Chinese Mind-Body Exercise Baduanjin Modulate Gray Matter and Cognitive Function in Older Adults with Mild Cognitive Impairment: A Brain Imaging Study.Brain plasticity (Amsterdam, Netherlands) · 2021Article
- Accelerometer Physical Activity is Associated with Greater Gray Matter Volumes in Older Adults Without Dementia or Mild Cognitive Impairment.The journals of gerontology. Series B, Psychological sciences and social sciences · 2019Article
- Immunological and Neurometabolite Changes Associated With Switch From Efavirenz to an Integrase Inhibitor.Journal of acquired immune deficiency syndromes (1999) · 2019Article
- Ketone Bodies in Neurological Diseases: Focus on Neuroprotection and Underlying Mechanisms.Frontiers in neurology · 2019Review
- Altered brain metabolites in patients with diabetes mellitus and related complications - evidence fromBioscience reports · 2018Review
- Neuroimaging Biomarkers of mTOR Inhibition on Vascular and Metabolic Functions in Aging Brain and Alzheimer's Disease.Frontiers in aging neuroscience · 2018Review
- Neuroimaging Biomarkers of Caloric Restriction on Brain Metabolic and Vascular Functions.Current nutrition reports · 2017Article
- Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2017Article
- (1)H-MRS metabolites in adults with Down syndrome: Effects of dementia.NeuroImage. Clinical · 2016Article
- Alzheimer's disease: Unique markers for diagnosis & new treatment modalities.The Indian journal of medical research · 2015Review
- Multimodal neuroimaging computing: a review of the applications in neuropsychiatric disorders.Brain informatics · 2015Review
- Caloric restriction increases ketone bodies metabolism and preserves blood flow in aging brain.Neurobiology of aging · 2015Article
- Early Shifts of Brain Metabolism by Caloric Restriction Preserve White Matter Integrity and Long-Term Memory in Aging Mice.Frontiers in aging neuroscience · 2015Article
- What have novel imaging techniques revealed about metabolism in the aging brain?Future neurology · 2014Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Multimodal magnetic resonance imaging (MRI) techniques have been developed to noninvasively measure structural, metabolic, hemodynamic and functional changes of the brain. These advantages have made MRI an important tool to investigate neurodegenerative disorders, including diagnosis, disease progression monitoring, and treatment efficacy evaluation. This paper discusses recent findings of the multimodal MRI in the context of surrogate biomarkers for identifying the risk for AD in normal cognitive (NC) adults, brain anatomical and functional alterations in amnestic mild cognitive impairment (aMCI), and Alzheimer's disease (AD) patients. Further developments of these techniques and the establishment of promising neuroimaging biomarkers will enhance our ability to diagnose aMCI and AD in their early stages and improve the assessment of therapeutic efficacy in these diseases in future clinical trials.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.