ArticlePloS one2011
Protective role of heme oxygenase-1 in Listeria monocytogenes-induced abortion.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Inhibition of Heme Oxygenase-1 by Zinc Protoporphyrin IX Improves Adverse Pregnancy Outcomes in Malaria During Early Gestation.Frontiers in immunology · 2022Article
- An Update Review on Listeria Infection in Pregnancy.Infection and drug resistance · 2021Review
- Heme Oxygenase-1 Induction in Human BeWo Trophoblast Cells DecreasesFrontiers in microbiology · 2021Article
- Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens.Antioxidants (Basel, Switzerland) · 2020Review
- Article
- Tim-3 inhibits macrophage control of Listeria monocytogenes by inhibiting Nrf2.Scientific reports · 2017Article
- Article
- Heme-Oxygenase-1 Expression Contributes to the Immunoregulation Induced byFrontiers in immunology · 2017Article
- Heme oxygenase/carbon monoxide in the female reproductive system: an overlooked signalling pathway.International journal of biochemistry and molecular biology · 2017Review
- Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance.Immunology · 2016Review
- Heme Oxygenase-1 Regulates Inflammation and Mycobacterial Survival in Human Macrophages during Mycobacterium tuberculosis Infection.Journal of immunology (Baltimore, Md. : 1950) · 2016Article
- NLRP3 inflammasome activation contributes to Listeria monocytogenes-induced animal pregnancy failure.BMC veterinary research · 2016Article
- Interferon γ-induced GTPase promotes invasion of Listeria monocytogenes into trophoblast giant cells.Scientific reports · 2015Article
- Heme oxygenase and the immune system in normal and pathological pregnancies.Frontiers in pharmacology · 2015Article
- Inactivation of the MAPK signaling pathway by Listeria monocytogenes infection promotes trophoblast giant cell death.Frontiers in microbiology · 2015Article
- The heme oxygenases: important regulators of pregnancy and preeclampsia.American journal of physiology. Regulatory, integrative and comparative physiology · 2014Review
- Heme oxygenase-1 is critically involved in placentation, spiral artery remodeling, and blood pressure regulation during murine pregnancy.Frontiers in pharmacology · 2014Article
- Effects of heme oxygenase-1 on innate and adaptive immune responses promoting pregnancy success and allograft tolerance.Frontiers in pharmacology · 2014Review
- Heme oxygenase in pregnancy and preeclampsia.Current opinion in nephrology and hypertension · 2013Review
- Regulation of inducible heme oxygenase and cyclooxygenase isozymes in a mouse model of spotted fever group rickettsiosis.Microbial pathogenesis · 2012Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well-known fact that various pathogens, including bacteria, virus, and protozoa, induce abortion in humans and animals. However the mechanisms of infectious abortion are little known. In this study, we demonstrated that Listeria monocytogenes infection in trophoblast giant cells decreased heme oxygenase (HO)-1 and B-cell lymphoma-extra large (Bcl-XL) expression, and that their overexpression inhibited cell death induced by the infection. Furthermore, HO-1 and Bcl-XL expression levels were also decreased by L. monocytogenes in pregnant mice. Treatment with cobalt protoporphyrin, which is known to induce HO-1, inhibited infectious abortion. Taken together, our study indicates that L. monocytogenes infection decreases HO-1 and Bcl-XL expression and induces cell death in placenta, leading to infectious abortion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.