Evidence map›Paper›PMID 21949565›Full record

ArticleCurrent cardiovascular imaging reports2011

Optical Coherence Tomography and Fibrous Cap Characterization.

Daniel Chamié, Zhao Wang, Hiram Bezerra, Andrew M Rollins, Marco A Costa

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Current cardiovascular imaging reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01743872 (Optical Imaging Measurement of Intravascular Solution Efficacy Trial), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01743872 nacompletednot on this mapstarted 2012, after this paper: background citation

Optical Imaging Measurement of Intravascular Solution Efficacy Trial

TypeinterventionalSponsorUniversity Hospitals Cleveland Medical CenterRan2012 to 2016Enrolled23ConditionsPeripheral Artery DiseaseArmsContrast Injection, Dextran Injection, CO2 Injection, Heparinized Normal Saline Injection
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Pathophysiology of Atherosclerosis.International journal of molecular sciences · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Guidance Molecules in Vascular Smooth Muscle.Frontiers in physiology · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel Chamié
Zhao Wang
Hiram Bezerra
Andrew M Rollins
Marco A Costa
Case Western Reserve University · USUniversity Hospitals Case Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathophysiology of acute coronary syndromes has long been associated with atherosclerotic plaque rupture. Inflammation, thinning, and disruption of the fibrous cap have been implicated with the final processes leading to plaque rupture, but confirmation of these mechanisms of coronary thrombosis in humans has been hampered by the lack of imaging methods with sufficient resolution to resolve fibrous cap characterization and thickness in vivo. Intravascular optical coherence tomography (OCT) provides images with micron-level axial and lateral resolution, enabling detailed visualization of micro-structural changes of the arterial wall. The present article provides an overview of the potential role of OCT in identifying and characterizing fibrous cap morphology, thickness, and inflammation in human coronary plaques.

Identifiers

PMID21949565
PMCPMC3158849
OpenAlexW2020271047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.