ReviewMuscle & nerve2011
Structure and function of the skeletal muscle extracellular matrix.
Review in Muscle & nerve, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03521778 (Fascial Distortion Model Manual Therapy and Painful Shoulder Syndrome), which is not on this map. Cited by 488 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Fascial Distortion Model Manual Therapy and Painful Shoulder Syndrome
Who cites it
488 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Skeletal muscle alterations in Marfan syndrome: a systematic review.Journal of muscle research and cell motility · 2025Pooled it
- Alterations in intramuscular connective tissue in hypertonic muscle: a scoping review.Frontiers in physiology · 2025Pooled it
- Effect of knee and hip joint positions on passive stiffness of the rectus femoris and vastus lateralis in healthy individuals.Scientific reports · 2026Trial
- Impact of gelatin supplementation on indices of skeletal muscle recovery: a pilot study.European journal of applied physiology · 2026Trial
- Effects of Reduced Training Volume of Nordic Hamstring Exercise on Eccentric Knee Flexor Strength, and Fascicle Length and Stiffness of Biceps Femoris Long Head.Scandinavian journal of medicine & science in sports · 2025Trial
- The nucleus as a mechanobiological hub in muscle aging.Nucleus (Austin, Tex.) · 2026Review
- Pathogenic transcriptional reprogramming of fibro-adipogenic progenitors in mice with FOP and its mitigation by inhibition of ACVR1 and activin A.bioRxiv : the preprint server for biology · 2026Article
- Thoracolumbar Fascia Remodeling in Lumbar Spinal Stenosis: Translational Orthopedic Perspectives.International journal of molecular sciences · 2026Article
- Integrating and Orchestrating Multiple Components of Skeletal Muscle Injury and Regeneration.American journal of physiology. Cell physiology · 2026Article
- The hallmarks of skeletal muscle health.Nature metabolism · 2026Review
- Medial gastrocnemius stiffness contributes to active ankle joint stiffness and ground contact time in trained track-and-field athletes.European journal of applied physiology · 2026Article
- Urinary proteomic signature of exercise intolerance in patients at risk of heart failure: evidence from the HOMAGE trial.EBioMedicine · 2026Article
- From Athletic Performance to Functional Ageing: Shared Genetic Architecture, Redox-Inflammatory Pathways and Functional Reserve Across the Life Course-A Narrative Review.Biomedicines · 2026Review
- Targeting muscle fibrosis using non-specific collagenase injections destabilizes the basal lamina and induces matrix remodeling.Skeletal muscle · 2026Article
- Application of ECIS to Evaluate the Effects of Porcine Urinary Bladder Matrix Hydrogels on Caco-2 Cell Attachment, Migration, and Barrier Formation.Gels (Basel, Switzerland) · 2026Article
- Aligned multicompartment collagen scaffolds support stratified myoblast and fibroblast behavior for musculotendinous tissue engineering.bioRxiv : the preprint server for biology · 2026Article
- Multiscale Modeling and Analysis of Muscle Tissue: A Finite Element Approach for 3D Braided Composite Structures.Biomimetics (Basel, Switzerland) · 2026Article
- Decoding cellular communication networks and signaling pathways in bone, skeletal muscle, and bone-muscle crosstalk through spatial transcriptomics in a young male mouse.Bone research · 2026Article
- Isolating and Validating Fibroblast-like Cells from the Skeletal Muscle of the Siamese Crocodile (Veterinary sciences · 2026Article
- Emergent directional persistence in fibrous granular scaffolds guides myotube organization.bioRxiv : the preprint server for biology · 2026Article
428 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The skeletal muscle extracellular matrix (ECM) plays an important role in muscle fiber force transmission, maintenance, and repair. In both injured and diseased states, ECM adapts dramatically, a property that has clinical manifestations and alters muscle function. Here we review the structure, composition, and mechanical properties of skeletal muscle ECM; describe the cells that contribute to the maintenance of the ECM; and, finally, overview changes that occur with pathology. New scanning electron micrographs of ECM structure are also presented with hypotheses about ECM structure–function relationships. Detailed structure–function relationships of the ECM have yet to be defined and, as a result, we propose areas for future study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.