Evidence map›Paper›PMID 21949429›Full record

ArticlePsychosomatic medicine2011

Medical comorbidity of full and partial posttraumatic stress disorder in US adults: results from Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions.

Robert H Pietrzak, Risë B Goldstein, Steven M Southwick, Bridget F Grant

Open access · greenAbstract readComparative Study
In one paragraph

Article in Psychosomatic medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 3 pooled it
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 3 syntheses or guidelines pooled it, 179 citations in OpenAlex.

  1. Pooled it
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  3. Association between posttraumatic stress disorder and lack of exercise, poor diet, obesity, and co-occuring smoking: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018
    Pooled it
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  18. Neural correlates linking trauma and physical symptoms.Psychiatry research. Neuroimaging · 2022
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  20. Abnormal intestinal milieu in posttraumatic stress disorder is not impacted by treatment that improves symptoms.American journal of physiology. Gastrointestinal and liver physiology · 2022
    Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Robert H PietrzakNational Center for Posttraumatic Stress Disorder, VA Connecticut Healthcare System, 950 Campbell Ave 151/E, West Haven, CT 06516, USA. robert.pietrzak@yale.edu
Risë B Goldstein
Steven M Southwick
Bridget F Grant
VA Connecticut Healthcare System · US

Funding

National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) - IIIZIAAA000449 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GRANT, BRIDGET F · 2009 to 2016
$16.5M
Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)Z01AA000449 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI GRANT, BRIDGET F · 2005 to 2008
$4.3M
Intramural NIH HHS Z01 AA000449
6 · The paper itself

Abstract

objectiveThis study examined associations between lifetime trauma exposures, PTSD and partial PTSD, and past-year medical conditions in a nationally representative sample of US adults.

methodsFace-to-face interviews were conducted with 34,653 participants in the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions. Logistic regression analyses evaluated associations of trauma exposure, PTSD, and partial PTSD with respondent-reported medical diagnoses.

resultsAfter adjustment for sociodemographic characteristics and comorbid Axis I and II disorders, respondents with full PTSD were more likely than traumatized respondents without full or partial PTSD (comparison group) to report diagnoses of diabetes mellitus, noncirrhotic liver disease, angina pectoris, tachycardia, hypercholesterolemia, other heart disease, stomach ulcer, human immunodeficiency virus seropositivity, gastritis, and arthritis (odds ratios [ORs] = 1.2-2.5). Respondents with partial PTSD were more likely than the comparison group to report past-year diagnoses of stomach ulcer, angina pectoris, tachycardia, and arthritis (ORs = 1.3-1.6). Men with full and partial PTSD were more likely than controls to report diagnoses of hypertension (both ORs = 1.6), and both men and women with PTSD (OR = 1.8 and OR = 1.6, respectively) and men with partial PTSD (OR = 2.0) were more likely to report gastritis. The total number of lifetime traumatic event types was associated with many assessed medical conditions (ORs = 1.04-1.16), reducing the magnitudes and rendering some of the associations between PTSD status and medical conditions nonsignificant.

conclusionsGreater lifetime trauma exposure and PTSD are associated with numerous medical conditions, many of which are stress-related and chronic, in US adults. Partial PTSD is associated with intermediate odds of some of these conditions.

Indexed as

AdultAgedAlcohol DrinkingComorbidityFemaleHealth SurveysHumansMaleMiddle AgedStress Disorders, Post-TraumaticUnited StatesYoung Adult

Identifiers

PMID21949429
PMCPMC3188699
OpenAlexW2082133381

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.