Evidence map›Paper›PMID 21948792›Full record

ArticleNucleic acids research2012

BμG@Sbase--a microbial gene expression and comparative genomic database.

Adam A Witney, Denise E Waldron, Lucy A Brooks, Richard H Tyler, Michael Withers, Neil G Stoker, Brendan W Wren, Philip D Butcher, Jason Hinds

Abstract read
In one paragraph

Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adam A WitneyBacterial Microarray Group, Centre for Infection & Immunity, Division of Clinical Sciences, St George's, University of London, Cranmer Terrace, London SW17 0RE, UK. awitney@sgul.ac.uk
Denise E Waldron
Lucy A Brooks
Richard H Tyler
Michael Withers
Neil G Stoker
Brendan W Wren
Philip D Butcher
Jason Hinds

Funding

Medical Research Council G0300020Wellcome Trust 062511Wellcome Trust 080039Wellcome Trust 086547
6 · The paper itself

Abstract

The reducing cost of high-throughput functional genomic technologies is creating a deluge of high volume, complex data, placing the burden on bioinformatics resources and tool development. The Bacterial Microarray Group at St George's (BμG@S) has been at the forefront of bacterial microarray design and analysis for over a decade and while serving as a hub of a global network of microbial research groups has developed BμG@Sbase, a microbial gene expression and comparative genomic database. BμG@Sbase (http://bugs.sgul.ac.uk/bugsbase/) is a web-browsable, expertly curated, MIAME-compliant database that stores comprehensive experimental annotation and multiple raw and analysed data formats. Consistent annotation is enabled through a structured set of web forms, which guide the user through the process following a set of best practices and controlled vocabulary. The database currently contains 86 expertly curated publicly available data sets (with a further 124 not yet published) and full annotation information for 59 bacterial microarray designs. The data can be browsed and queried using an explorer-like interface; integrating intuitive tree diagrams to present complex experimental details clearly and concisely. Furthermore the modular design of the database will provide a robust platform for integrating other data types beyond microarrays into a more Systems analysis based future.

Indexed as

Databases, GeneticGene Expression ProfilingGenome, BacterialOligonucleotide Array Sequence AnalysisGene ExpressionGenomicsMolecular Sequence AnnotationUser-Computer Interface

Identifiers

PMID21948792
PMCPMC3245117

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.