Evidence map›Paper›PMID 21948062›Full record

ReviewMycopathologia2012

Ten challenges on Cryptococcus and cryptococcosis.

Maurizio Del Poeta, Arturo Casadevall

Abstract readReview
In one paragraph

Review in Mycopathologia, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Article
  3. Promising immunotherapeutic targets for treating candidiasis.Frontiers in cellular and infection microbiology · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. The Antimicrobial Peptide MK58911-NHAntimicrobial agents and chemotherapy · 2021
    Article
  9. Review
  10. Article
  11. Disseminated cryptococcosis in an immunocompetent patient.Respiratory medicine case reports · 2020
    Article
  12. Animal Models ofFrontiers in immunology · 2020
    Review
  13. Review
  14. Article
  15. Evaluation of Vitek MS for Differentiation ofJournal of clinical microbiology · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maurizio Del PoetaDepartment of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, SC 29425, USA. delpoeta@musc.edu
Arturo Casadevall

Funding

Synergy of Host Defense Mechanisms in the LungR01HL059842 · NHLBI · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1997 to 2023
$7.4M
Biology of Fungal MelaninR01AI052733 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 2003 to 2019
$6.6M
PROTECTIVE ANTIBODIES FOR CRYPTOCOCCAL INFECTIONSR01AI033774 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1994 to 2014
$5.6M
Molecular Characterization of C. neoformans AntibodiesR37AI033142 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CASADEVALL, ARTURO · 2007 to 2016
$3.9M
Sphingolipid-mediated fungal pathogenesisR01AI056168 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2004 to 2013
$2.7M
Role of phagocytosis in pathogenesis of Cryptococcus neorformansR01AI071142 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI DEL POETA, MAURIZIO · 2008 to 2012
$1.7M
MOLECULAR CHARACTERIZATION OF C NEOFORMANS ANTIBODIESR01AI033142 · NIAID · YESHIVA UNIVERSITY · PI CASADEVALL, ARTURO · 1994 to 2006
$1.7M
New methods for the early diagnosis of invasive fungal infectionsR21AI078493 · NIAID · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DEL POETA, MAURIZIO · 2008 to 2009
$406k
Host sphingolipids and fungal infectionR56AI087541 · NIAID · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HAMA, HIROKO · 2011 to 2011
$383k
NHLBI NIH HHS HL059842NHLBI NIH HHS R01 HL059842NIAID NIH HHS AI033142NIAID NIH HHS AI033774NIAID NIH HHS AI052733NIAID NIH HHS AI056168NIAID NIH HHS AI071142NIAID NIH HHS AI078493NIAID NIH HHS AI087541NIAID NIH HHS R01 AI033142NIAID NIH HHS R01 AI033774NIAID NIH HHS R01 AI052733NIAID NIH HHS R01 AI056168NIAID NIH HHS R01 AI071142NIAID NIH HHS R21 AI078493NIAID NIH HHS R37 AI033142NIAID NIH HHS R56 AI087541
6 · The paper itself

Abstract

Cryptococcosis has become a significant public global health problem worldwide. Caused by two species, Cryptococcus neoformans or Cryptococcus gattii, this life-threatening infection afflicts not only immunocompromised individuals but also apparently immunocompetent subjects. Hence, cryptococcosis should no longer be considered merely an opportunistic infection. In this article, we focus on ten unanswered questions/topics in this field with the hope to stimulate discussion and research on these topics that would lead not only to a better understanding of the physiopathology of this disease but also to a better diagnosis and prognosis.

Indexed as

Host-Pathogen InteractionsBiomedical ResearchCryptococcosisCryptococcus gattiiCryptococcus neoformansHumansVirulence

Identifiers

PMID21948062
PMCPMC4294698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.