Evidence map›Paper›PMID 21947116›Full record

ReviewNature reviews. Nephrology2011

Nutrition and growth in children with chronic kidney disease.

Lesley Rees, Robert H Mak

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06268314 (Feeding Pattern and Hypoalbuminemia in Pediatrics With Chronic Kidney Disease.), which is not on this map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06268314 unknown statusnot on this mapstarted 2024, after this paper: background citation

Feeding Pattern and Hypoalbuminemia in Pediatrics With Chronic Kidney Disease.

TypeobservationalSponsorAssiut UniversityRan2024 to 2026Enrolled70ConditionsChronic Kidney Diseases
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Chronic Kidney Disease and Growth Failure in Children.Children (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Review
  10. Chronic kidney disease in children: an update.Clinical kidney journal · 2023
    Review
  11. Article
  12. Article
  13. Mineral Metabolism in Children: Interrelation between Vitamin D and FGF23.International journal of molecular sciences · 2023
    Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lesley ReesDepartment of Nephrology, Great Ormond Street Hospital for Children National Health Service Trust, Great Ormond Street, London WC1N 3JH, UK.
Robert H Mak
University of California, San Diego · US

Funding

NIDDK NIH HHS U01 DK-03-012
6 · The paper itself

Abstract

Poor growth in chronic kidney disease (CKD) is a marker of disease severity and of quality of care. Causes are multifactorial, and include malnutrition, cachexia, hematological factors, endocrine problems and metabolic abnormalities. In this Review, we focus on the impact of inadequate nutrition on growth disturbances in children with CKD, and discuss all aspects of the epidemiology, causes and potential treatments. Regional variations in resources may be a factor that contributes to the observed differences. Successful nutritional management requires a multidisciplinary team that includes not only doctors but also skilled nurses and dieticians. Extremes of body mass index, representing undernutrition and overnutrition, are associated with poor outcomes and should be avoided when designing therapeutic strategies for optimizing nutrition and growth in children with CKD. Improved understanding of the pathophysiology of cachexia and wasting in patients with CKD could lead to the development of novel therapeutic strategies.

Indexed as

ChildChild DevelopmentChild Nutrition DisordersGrowth DisordersHumansRenal Insufficiency, Chronic

Identifiers

PMID21947116
OpenAlexW1972336462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.