ReviewThrombosis and haemostasis2011
Natural killer T cells in lipoprotein metabolism and atherosclerosis.
Review in Thrombosis and haemostasis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Apolipoprotein E in Cardiometabolic and Neurological Health and Diseases.International journal of molecular sciences · 2022Review
- Cellular Immune Dysfunction in Obstructive Sleep Apnea.Frontiers in surgery · 2022Review
- Microarray and proteome array in an atherosclerosis mouse model for identification of biomarkers in whole blood.International journal of medical sciences · 2019Article
- Natural killer T cells in atherosclerosis.Nature reviews. Cardiology · 2017Review
- Animal models of atherosclerosis.Biomedical reports · 2017Article
- Mouse models of atherosclerosis: a historical perspective and recent advances.Lipids in health and disease · 2017Review
- Tailoring Nanostructure Morphology for Enhanced Targeting of Dendritic Cells in Atherosclerosis.ACS nano · 2016Article
- Engineering nanomaterials to address cell-mediated inflammation in atherosclerosis.Regenerative engineering and translational medicine · 2016Article
- Article
- Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model.Nature communications · 2015Article
- Mesenchymal stem cells alleviate atherosclerosis by elevating number and function of CD4(+)CD25 (+)FOXP3 (+) regulatory T-cells and inhibiting macrophage foam cell formation.Molecular and cellular biochemistry · 2015Article
- T, B, and NKT Cells in Systemic Inflammation in Obstructive Sleep Apnoea.Mediators of inflammation · 2015Article
- The CD1d-natural killer T cell axis in atherosclerosis.Journal of innate immunity · 2014Review
- The influence of innate and adaptive immune responses on atherosclerosis.Annual review of pathology · 2014Review
- Increased levels of invariant natural killer T lymphocytes worsen metabolic abnormalities and atherosclerosis in obese mice.Journal of lipid research · 2013Article
- Direct identification of rat iNKT cells reveals remarkable similarities to human iNKT cells and a profound deficiency in LEW rats.European journal of immunology · 2013Article
- Adaptive immunity in atherogenesis: new insights and therapeutic approaches.The Journal of clinical investigation · 2013Review
- Lymphocytes in obesity-related adipose tissue inflammation.Diabetologia · 2012Review
- Animal models of atherosclerosis.Arteriosclerosis, thrombosis, and vascular biology · 2012Review
- Interplay between carbohydrate and lipid in recognition of glycolipid antigens by natural killer T cells.Annals of the New York Academy of Sciences · 2012Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cells of both the innate and adaptive immune system participate in the development of atherosclerosis, a chronic inflammatory disorder of medium and large arteries. Natural killer T (NKT) cells express surface markers characteristic of natural killer cells and conventional T cells and bridge the innate and adaptive immune systems. The development and activation of NKT cells is dependent upon CD1d, a MHC-class I-type molecule that presents lipids, especially glycolipids to the T cell receptors on NKT cells. There are two classes of NKT cells; invariant NKT cells that express a semi-invariant T cell receptor and variant NKT cells. This review summarises studies in murine models in which the effect of the activation, overexpression or deletion of NKT cells or only invariant NKT cells on atherosclerosis has been examined.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.