ArticleNature neuroscience2011
Neural activity at the human olfactory epithelium reflects olfactory perception.
Article in Nature neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Effects of 20 mg oral Δ(9) -tetrahydrocannabinol on the olfactory function of healthy volunteers.British journal of clinical pharmacology · 2014Trial
- Age-related changes in olfactory function: electrophysiological recordings from the olfactory mucosa and human brain.npj aging · 2026Article
- Odor Thresholds in Flavor Science: A Data-Driven Review From Mechanisms to Applications.Comprehensive reviews in food science and food safety · 2026Review
- The Unmet Need of Olfactory Testing in Inflammatory Disorders of the Upper Airways-An EAACI Position Paper.Allergy · 2026Review
- Investigating the flavor contributions of sulfur compounds in soy sauce flavor Baijiu using flavoromics and machine learning.NPJ science of food · 2026Article
- Separable and integrated pleasantness coding for appetitive and aversive odors across olfactory and ventral prefrontal cortices.Nature communications · 2026Article
- Direct perception of affective valence from vision.Nature communications · 2024Article
- A deep position-encoding model for predicting olfactory perception from molecular structures and electrostatics.NPJ systems biology and applications · 2024Article
- High-precision mapping reveals the structure of odor coding in the human brain.Nature neuroscience · 2023Article
- Physicochemical features partially explain olfactory crossmodal correspondences.Scientific reports · 2023Article
- Incidence of Anosmia among Covid 19 patients in India.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022Article
- International consensus statement on allergy and rhinology: Olfaction.International forum of allergy & rhinology · 2022Review
- Article
- Odor hedonics coding in the vertebrate olfactory bulb.Cell and tissue research · 2021Review
- Quantitative assessment of olfactory dysfunction accurately detects asymptomatic COVID-19 carriers.EClinicalMedicine · 2020Article
- Alzheimer's Disease: What Can We Learn From the Peripheral Olfactory System?Frontiers in neuroscience · 2020Review
- The role of hedonics in the Human Affectome.Neuroscience and biobehavioral reviews · 2019Review
- Chemical features mining provides new descriptive structure-odor relationships.PLoS computational biology · 2019Article
- Machine Learning in Human Olfactory Research.Chemical senses · 2019Review
- Implications for human odor sensing revealed from the statistics of odorant-receptor interactions.PLoS computational biology · 2018Article
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8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organization of receptive surfaces reflects primary axes of perception. In vision, retinal coordinates reflect spatial coordinates. In audition, cochlear coordinates reflect tonal coordinates. However, the rules underlying the organization of the olfactory receptive surface are unknown. To test the hypothesis that organization of the olfactory epithelium reflects olfactory perception, we inserted an electrode into the human olfactory epithelium to directly measure odorant-induced evoked responses. We found that pairwise differences in odorant pleasantness predicted pairwise differences in response magnitude; that is, a location that responded maximally to a pleasant odorant was likely to respond strongly to other pleasant odorants, and a location that responded maximally to an unpleasant odorant was likely to respond strongly to other unpleasant odorants. Moreover, the extent of an individual's perceptual span predicted their span in evoked response. This suggests that, similarly to receptor surfaces for vision and audition, organization of the olfactory receptor surface reflects key axes of perception.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.