ArticlePhysiology & behavior2012
Disruption of urinary odor preference and lordosis behavior in female mice given lesions of the medial amygdala.
Article in Physiology & behavior, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 51 citations in OpenAlex.
- IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: Rodent reproductive behavior among males and females after exposure to endocrine-disrupting chemicals.Reproduction (Cambridge, England) · 2024Review
- Neural control of female sexual behaviors.Hormones and behavior · 2023Review
- Sex differences in the coexpression of prokineticin receptor 2 and gonadal steroids receptors in mice.Frontiers in neuroanatomy · 2022Article
- Posterodorsal Medial Amygdala Regulation of Female Social Behavior: GABA versus Glutamate Projections.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Neural and Hormonal Basis of Opposite-Sex Preference by Chemosensory Signals.International journal of molecular sciences · 2021Review
- Organization of neural circuits underlying social behavior: A consideration of the medial amygdala.Current opinion in neurobiology · 2021Review
- Human Primary Olfactory Amygdala Subregions Form Distinct Functional Networks, Suggesting Distinct Olfactory Functions.Frontiers in systems neuroscience · 2021Article
- Neural and Hormonal Control of Sexual Behavior.Endocrinology · 2020Review
- Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases luteinising hormone pulse frequency in female mice.Journal of neuroendocrinology · 2020Article
- Developmental origins of sex differences in the neural circuitry of play.International journal of play · 2020Article
- Estradiol-Dependent and -Independent Stimulation of Kiss1 Expression in the Amygdala, BNST, and Lateral Septum of Mice.Endocrinology · 2018Article
- Kisspeptin neurones in the posterodorsal medial amygdala modulate sexual partner preference and anxiety in male mice.Journal of neuroendocrinology · 2018Article
- Effect of Ovarian Hormones and Mating Experience on the Preference of Female Mice to Investigate Male Urinary Pheromones.Chemical senses · 2018Article
- Synchronized Activity in The Main and Accessory Olfactory Bulbs and Vomeronasal Amygdala Elicited by Chemical Signals in Freely Behaving Mice.Scientific reports · 2017Article
- DREADD-induced silencing of the medial amygdala reduces the preference for male pheromones and the expression of lordosis in estrous female mice.The European journal of neuroscience · 2017Article
- Nrp2 is sufficient to instruct circuit formation of mitral-cells to mediate odour-induced attractive social responses.Nature communications · 2017Article
- A comparison of the effects of male pheromone priming and optogenetic inhibition of accessory olfactory bulb forebrain inputs on the sexual behavior of estrous female mice.Hormones and behavior · 2017Article
- Regulation and Possible Functions of Kisspeptin in the Medial Amygdala.Frontiers in endocrinology · 2017Review
- Estrogen Stimulation of Kiss1 Expression in the Medial Amygdala Involves Estrogen Receptor-α But Not Estrogen Receptor-β.Endocrinology · 2016Article
- Molecular and neural control of sexually dimorphic social behaviors.Current opinion in neurobiology · 2016Review
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Previous research showed that axonal inputs to both anterior and posterior subdivisions of the medial amygdala from the main and accessory olfactory bulbs of female mice, respectively, process volatile and non-volatile pheromonal signals from male conspecifics. In the present study we found that bilateral electrolytic lesions that included posterior portions, but not the anterior subdivision alone of the medial amygdala (Me) blocked the preference of estrous female mice to investigate volatile urinary odors from testes-intact vs. castrated males. Similar results were obtained in separate tests in which nasal contact with urinary stimuli was permitted. In addition, total time investigating volatile urinary stimuli was reduced in subjects with posterior Me lesions. Subjects were able to discriminate volatile urinary odors from testes-intact vs. castrated male mice, suggesting that this disruption of odor preference did not result from the inability of females given amygdaloid lesions to discriminate these male urinary odors. Bilateral lesions of the Me that were either restricted to the anterior or posterior subdivisions, or included areas of both regions, caused significant reductions in the display of lordosis behavior in estrous female mice. Our results suggest that the Me is a critical segment of the olfactory circuit that controls both mate recognition and mating behavior in the female mouse.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.