ArticleAmerican journal of human genetics2011
Denisova admixture and the first modern human dispersals into Southeast Asia and Oceania.
Article in American journal of human genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 195 papers.
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195 citing papers in PubMed, 674 citations in OpenAlex.
- Article
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- Insights into human adaptation from ancient DNA.Nature genetics · 2026Review
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
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- Resolving out of Africa event for Papua New Guinean population using neural network.Nature communications · 2025Article
- A rare splice-site variant in TNNT2: the need for ancestral diversity in genomic reference data sets.European heart journal · 2025Article
- Population genomics advances in frontier ethnic minorities in China.Science China. Life sciences · 2025Review
- Dentition of the Mugharet El'Aliya Fossil Human Maxilla, Morocco.American journal of biological anthropology · 2025Article
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- A near-continuous archaeological record of Pleistocene human occupation at Leang Bulu Bettue, Sulawesi, Indonesia.PloS one · 2025Article
- A history of multiple Denisovan introgression events in modern humans.Nature genetics · 2024Review
- More than a decade of genetic research on the Denisovans.Nature reviews. Genetics · 2024Review
- Leveraging shared ancestral variation to detect local introgression.PLoS genetics · 2024Article
- Hunter-gatherer genetics research: Importance and avenues.Evolutionary human sciences · 2024Article
- Palaeoenvironments and hominin evolutionary dynamics in southeast Asia.Scientific reports · 2023Article
- Article
- Genomic history of coastal societies from eastern South America.Nature ecology & evolution · 2023Article
- Evolutionary Origin of HumanInternational journal of molecular sciences · 2023Article
135 more citing papers are in PubMed but not listed here.
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Authors and funding
15 authors at 8 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has recently been shown that ancestors of New Guineans and Bougainville Islanders have inherited a proportion of their ancestry from Denisovans, an archaic hominin group from Siberia. However, only a sparse sampling of populations from Southeast Asia and Oceania were analyzed. Here, we quantify Denisova admixture in 33 additional populations from Asia and Oceania. Aboriginal Australians, Near Oceanians, Polynesians, Fijians, east Indonesians, and Mamanwa (a "Negrito" group from the Philippines) have all inherited genetic material from Denisovans, but mainland East Asians, western Indonesians, Jehai (a Negrito group from Malaysia), and Onge (a Negrito group from the Andaman Islands) have not. These results indicate that Denisova gene flow occurred into the common ancestors of New Guineans, Australians, and Mamanwa but not into the ancestors of the Jehai and Onge and suggest that relatives of present-day East Asians were not in Southeast Asia when the Denisova gene flow occurred. Our finding that descendants of the earliest inhabitants of Southeast Asia do not all harbor Denisova admixture is inconsistent with a history in which the Denisova interbreeding occurred in mainland Asia and then spread over Southeast Asia, leading to all its earliest modern human inhabitants. Instead, the data can be most parsimoniously explained if the Denisova gene flow occurred in Southeast Asia itself. Thus, archaic Denisovans must have lived over an extraordinarily broad geographic and ecological range, from Siberia to tropical Asia.
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