ArticleBiophysical journal2011
Rigidity sensing explained by active matter theory.
Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Unified multiscale theory of cellular mechanical adaptations to substrate stiffness.Biophysical journal · 2022Article
- Sticking around: Cell adhesion patterning for energy minimization and substrate mechanosensing.Biophysical journal · 2022Article
- Collective durotaxis of cohesive cell clusters on a stiffness gradient.The European physical journal. E, Soft matter · 2022Article
- Computational models of migration modes improve our understanding of metastasis.APL bioengineering · 2020Review
- Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy.Science (New York, N.Y.) · 2020Article
- Nonuniform growth and surface friction determine bacterial biofilm morphology on soft substrates.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Mechanosensing in the immune response.Seminars in cell & developmental biology · 2017Review
- Dynamic Mechano-Regulation of Myoblast Cells on Supramolecular Hydrogels Cross-Linked by Reversible Host-Guest Interactions.Scientific reports · 2017Article
- The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction.Journal of biomechanical engineering · 2017Review
- Prediction of traction forces of motile cells.Interface focus · 2016Article
- The actin crosslinking protein palladin modulates force generation and mechanosensitivity of tumor associated fibroblasts.Scientific reports · 2016Article
- Front-Rear Polarization by Mechanical Cues: From Single Cells to Tissues.Trends in cell biology · 2016Review
- Cell shape dynamics reveal balance of elasticity and contractility in peripheral arcs.Biophysical journal · 2015Article
- Cells as liquid motors: mechanosensitivity emerges from collective dynamics of actomyosin cortex.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Cytoskeletal forces during signaling activation in Jurkat T-cells.Molecular biology of the cell · 2015Article
- Microglia mechanics: immune activation alters traction forces and durotaxis.Frontiers in cellular neuroscience · 2015Article
- Mechanotransduction and extracellular matrix homeostasis.Nature reviews. Molecular cell biology · 2014Review
- A time-dependent phenomenological model for cell mechano-sensing.Biomechanics and modeling in mechanobiology · 2014Article
- To pull or be pulled: parsing the multiple modes of mechanotransduction.Current opinion in cell biology · 2013Review
- Contractile fibers and catch-bond clusters: a biological force sensor?Biophysical journal · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The magnitude of traction forces exerted by living animal cells on their environment is a monotonically increasing and approximately sigmoidal function of the stiffness of the external medium. We rationalize this observation using active matter theory, and propose that adaptation to substrate rigidity results from an interplay between passive elasticity and active contractility.
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