Evidence map›Paper›PMID 21942677›Full record

ReviewChemical reviews2011

Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis.

William L Smith, Yoshihiro Urade, Per-Johan Jakobsson

Abstract readReview
In one paragraph

Review in Chemical reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 225 papers.

0numbers the graph read from it
0cells of the map it votes in
225citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

225 citing papers in PubMed.

  1. Lipocalin-type prostaglandin D synthase scavenges biliverdin in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2014
    Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Allosteric regulation of prostaglandin endoperoxide HThe Journal of biological chemistry · 2025
    Review
  13. Article
  14. COX-2 in Fracture Callus Chondro-Osseous Junction Osteoclasts Regulates Chondrocyte Hypertrophy and Callus Vasculogenesis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Urinary prostaglandin DScientific reports · 2025
    Article
  20. Article

165 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William L SmithDepartment of Biological Chemistry, University of Michigan Medical School, 1150 West Medical Center Drive, 5301 MSRB III, Ann Arbor, Michigan 48109-5606, USA. smithww@umich.edu
Yoshihiro Urade
Per-Johan Jakobsson

Funding

Catalysis by Prostaglandin Endoperoxide H SynthasesR01GM068848 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SMITH, WILLIAM L · 2003 to 2014
$5.6M
NIGMS NIH HHS GM68848NIGMS NIH HHS R01 GM068848
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansProstaglandin-Endoperoxide SynthasesProstaglandinsProstaglandin-Endoperoxide SynthasesProstaglandins

Identifiers

PMID21942677
PMCPMC3285496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.