ArticleBehavioral neuroscience2012
Estradiol-dependent modulation of serotonergic markers in auditory areas of a seasonally breeding songbird.
Article in Behavioral neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 37 citations in OpenAlex.
- Biological relevance and methodological implications of unexpected hearing thresholds in a diving bird.Scientific reports · 2024Article
- Estrogens rapidly shape synaptic and intrinsic properties to regulate the temporal precision of songbird auditory neurons.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Connecting gut microbiomes and short chain fatty acids with the serotonergic system and behavior inFrontiers in physiology · 2022Review
- Internal State: Dynamic, Interconnected Communication Loops Distributed Across Body, Brain, and Time.Integrative and comparative biology · 2021Article
- Molecular architecture of the zebra finch arcopallium.The Journal of comparative neurology · 2019Article
- Conditioned place preferences induced by hearing song outside the breeding season relate to neural dopamine DBehavioural brain research · 2019Article
- Sound-induced monoaminergic turnover in the auditory forebrain depends on endocrine state in a seasonally-breeding songbird.Journal of neuroendocrinology · 2018Article
- Review
- Putting it in Context: Linking Auditory Processing with Social Behavior Circuits in the Vertebrate Brain.Integrative and comparative biology · 2017Review
- Serotonin, estrus, and social context influence c-Fos immunoreactivity in the inferior colliculus.Behavioral neuroscience · 2016Article
- Seasonal variations in auditory processing in the inferior colliculus of Eptesicus fuscus.Hearing research · 2016Article
- Context-dependent fluctuation of serotonin in the auditory midbrain: the influence of sex, reproductive state and experience.The Journal of experimental biology · 2014Article
- Recent evidence for rapid synthesis and action of oestrogens during auditory processing in a songbird.Journal of neuroendocrinology · 2013Review
- Storing maternal memories: hypothesizing an interaction of experience and estrogen on sensory cortical plasticity to learn infant cues.Frontiers in neuroendocrinology · 2013Review
- Estrogenic modulation of auditory processing: a vertebrate comparison.Frontiers in neuroendocrinology · 2013Review
- Estradiol modulates neurotransmitter concentrations in the developing zebra finch song system.Brain research · 2013Article
- Functional changes between seasons in the male songbird auditory forebrain.Frontiers in behavioral neuroscience · 2013Article
- Estradiol selectively enhances auditory function in avian forebrain neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- From behavioral context to receptors: serotonergic modulatory pathways in the IC.Frontiers in neural circuits · 2012Article
- Rapid effects of hearing song on catecholaminergic activity in the songbird auditory pathway.PloS one · 2012Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Because no organism lives in an unchanging environment, sensory processes must remain plastic so that in any context, they emphasize the most relevant signals. As the behavioral relevance of sociosexual signals changes along with reproductive state, the perception of those signals is altered by reproductive hormones such as estradiol (E2). We showed previously that in white-throated sparrows, immediate early gene responses in the auditory pathway of females are selective for conspecific male song only when plasma E2 is elevated to breeding-typical levels. In this study, we looked for evidence that E2-dependent modulation of auditory responses is mediated by serotonergic systems. In female nonbreeding white-throated sparrows treated with E2, the density of fibers immunoreactive for serotonin transporter innervating the auditory midbrain and rostral auditory forebrain increased compared with controls. E2 treatment also increased the concentration of the serotonin metabolite 5-HIAA in the caudomedial mesopallium of the auditory forebrain. In a second experiment, females exposed to 30 min of conspecific male song had higher levels of 5-HIAA in the caudomedial nidopallium of the auditory forebrain than birds not exposed to song. Overall, we show that in this seasonal breeder, (a) serotonergic fibers innervate auditory areas; (b) the density of those fibers is higher in females with breeding-typical levels of E2 than in nonbreeding, untreated females; and (c) serotonin is released in the auditory forebrain within minutes in response to conspecific vocalizations. Our results are consistent with the hypothesis that E2 acts via serotonin systems to alter auditory processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.