Evidence map›Paper›PMID 21941647›Full record

ArticleInternational journal of molecular imaging2011

Towards in vivo imaging of cancer sialylation.

Ivan Martinez-Duncker, Roberta Salinas-Marin, Carlos Martinez-Duncker

Open access · hybridAbstract read
In one paragraph

Article in International journal of molecular imaging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Tumor Targeting via Sialic Acid: [Molecular imaging and biology · 2018
    Article
  6. Sialylation: an Avenue to Target Cancer Cells.Pathology oncology research : POR · 2016
    Review
  7. Review
  8. Chemoinformatic Study andIndian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ivan Martinez-DunckerHuman Glycobiology Laboratory, Science Faculty, Autonomous University of the State of Morelos, Avenida Universidad 1001, Col. Chamilpa, 62209 Cuernavaca, MOR, Mexico.
Roberta Salinas-Marin
Carlos Martinez-Duncker
Universidad Autónoma del Estado de Morelos · MXMexican Academy of Sciences · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo assessment of tumor glucose catabolism by positron emission tomography (PET) has become a highly valued study in the medical management of cancer. Emerging technologies offer the potential to evaluate in vivo another aspect of cancer carbohydrate metabolism related to the increased anabolic use of monosaccharides like sialic acid (Sia). Sia is used for the synthesis of sialylated oligosaccharides in the cell surface that in cancer cells are overexpressed and positively associated to malignancy and worse prognosis because of their role in invasion and metastasis. This paper addresses the key points of the different strategies that have been developed to image Sia expression in vivo and the perspectives to translate it from the bench to the bedside where it would offer the clinician highly valued complementary information on cancer carbohydrate metabolism that is currently unavailable in vivo.

Identifiers

PMID21941647
PMCPMC3175693
OpenAlexW2029086864

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.