ArticleOxidative medicine and cellular longevity2011
Ameliorative effects of herbal combinations in hyperlipidemia.
Article in Oxidative medicine and cellular longevity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Effect of co-administration of metformin and extracts ofJournal of traditional and complementary medicine · 2022Article
- Article
- Protective effect of Glycyrrhiza glabra roots extract on bone mineral density of ovariectomized rats.BioMedicine · 2019Article
- α-Amylase and α-glucosidase inhibitor effects and pancreatic response to diabetes mellitus on Wistar rats of Ephedra alata areal part decoction with immunohistochemical analyses.Environmental science and pollution research international · 2019Article
- Hypolipidemic effects of total flavonoide extracted from the leaves ofIranian journal of basic medical sciences · 2017Article
- Blood glucose level and lipid profile of alloxan-induced hyperglycemic rats treated with single and combinatorial herbal formulations.Journal of traditional and complementary medicine · 2016Article
- Chlorophytum borivilianum root extract maintains near normal blood glucose, insulin and lipid profile levels and prevents oxidative stress in the pancreas of streptozotocin-induced adult male diabetic rats.International journal of medical sciences · 2014Article
- Anti-oxidant and anti-hyperlipidemic activity ofAvicenna journal of phytomedicineArticle
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Authors and funding
2 authors.
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Abstract
The roots of Glycyrrhiza glabra, Withania somnifera, Asparagus racemosus, and Chlorophytum borivilianum and seeds of Sesamum indicum are ayurvedic medicinal plants used in India to treat several ailments. Our previous studies indicated that these plants possess hypolipidemic and antioxidant potential. The present study was aimed at investigating the composite effects of these plants on hypercholesterolemic rats. Three different combinations (5 gm%, given for four weeks) used in this study effectively reduced plasma and hepatic lipid profiles and increased fecal excretion of cholesterol, neutral sterol, and bile acid along with increasing the hepatic HMG-CoA reductase activity and bile acid content in hypercholesterolemic rats. Further, all three combinations also improved the hepatic antioxidant status (catalase, SOD, and ascorbic acid levels) and plasma total antioxidant capacity with reduced hepatic lipid peroxidation. Overall, combination I had the maximum effect on hypercholesterolemic rats followed by combinations II and III due to varying concentrations of the different classes of phytocomponents.
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