ArticleInternational journal of general medicine2011
Seasonal variation of vitamin D and HbA(1c) levels in patients with type 1 diabetes mellitus in the Middle East.
Article in International journal of general medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 24 citations in OpenAlex.
- Seasonal variation of HbA1c levels in diabetic and non-diabetic patients.Practical laboratory medicine · 2024Article
- Seasonal variation of glycated haemoglobin and estimated average glucose in temperate South Africa.Journal of the colleges of medicine of South Africa · 2024Article
- Vitamin D Related Gene Polymorphisms and Cholesterol Levels in a Mediterranean Population.Journal of cardiovascular development and disease · 2022Article
- Role of Placental VDR Expression and Function in Common Late Pregnancy Disorders.International journal of molecular sciences · 2017Review
- Variants in Vitamin D Binding Protein Gene Are Associated With Gestational Diabetes Mellitus.Medicine · 2015Observational
- Effect of vitamin d3 supplement in glycemic control of pediatrics with type 1 diabetes mellitus and vitamin d deficiency.Journal of clinical and diagnostic research : JCDR · 2015Article
- Year-round vitamin D deficiency among Saudi female out-patients.Public health nutrition · 2013Article
- The role of vitamin d deficiency in the incidence, progression, and complications of type 1 diabetes mellitus.International journal of endocrinology · 2013Article
- Seasonal variations in serum vitamin D according to age and sex.Caspian journal of internal medicine · 2012Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe discovery that many tissues express the vitamin D receptor and are able to transform the 25-hydroxyvitamin D into 1,25-dihydroxyvitamin D (active metabolite) has led to the hypothesis that vitamin D could have a role in the pathogenesis and prevention of diabetes mellitus. Accumulating evidence has linked vitamin D deficiency with immunological disturbance in type 1 diabetes mellitus. Several epidemiological studies have shown lower serum 25-hydroxyvitamin D concentrations in diabetic individuals compared to nondiabetic individuals. PATIENTS AND
methodsA total of 105 Lebanese patients with type 1 diabetes mellitus were recruited. Levels of HbA(1c) and vitamin D were recorded during two phases with phase 1 being the period from June-September 2009 and phase 2 from January-April 2009.
resultsVitamin D levels at the end of sunny season (phase 2), reflecting the previous sunny months, were found to be higher than in the early summer season (phase 1) reflecting the previous cloudy months season, with a mean change of 0.70 ± 6.87 ng/mL (P = 0.029). HbA(1c) levels were higher in phase 2 than in phase 1 with an increase of 0.175% ± 1.46% (P = 0.113).
conclusionVitamin D levels were higher at the end of the sunny season than at the end of cloudy season. HbA(1c) was also lower (but not significantly so) in the early summer season (cloudy months). There was a weak correlation between seasonal changes of vitamin D levels and the control of blood glucose as monitored by HbA(1c) in a cohort of Lebanese patients with type 1 diabetes mellitus.
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