Evidence map›Paper›PMID 21941090›Full record

ReviewHuman vaccines2011

Recent developments for Pseudomonas vaccines.

Anurag Sharma, Anja Krause, Stefan Worgall

Abstract readReview
In one paragraph

Review in Human vaccines, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
  2. Review
  3. Molecular Mechanisms Underlying the Pathogenicity ofMedicina (Kaunas, Lithuania) · 2026
    Review
  4. Review
  5. Antimicrobial resistance ofFrontiers in microbiology · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Vaccination to PreventFrontiers in microbiology · 2022
    Article
  16. Review
  17. RecombinantInfection and immunity · 2021
    Article
  18. Article
  19. Article
  20. AVaccines · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anurag SharmaDepartment of Genetic Medicine, Weill Medical College of Cornell University, New York, NY, USA.
Anja Krause
Stefan Worgall

Funding

Immunization Against Pseudomonas aeruginosa by Modified Ad VectorsU01AI069032 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI WORGALL, STEFAN · 2006 to 2010
$2.1M
Immunity Induced by Modified Adenovirus FiberR01AI072238 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI WORGALL, STEFAN · 2007 to 2011
$2.1M
NIAID NIH HHS R01 AI072238NIAID NIH HHS R01 AI72238NIAID NIH HHS U01 AI069032
6 · The paper itself

Abstract

Infections with Pseudomonas aeruginosa are a major health problem for immune-compromised patients and individuals with cystic fibrosis. A vaccine against: P. aeruginosa has long been sought after, but is so far not available. Several vaccine candidates have been assessed in experimental animals and humans, which include sub-cellular fractions, capsule components, purified and recombinant proteins. Unique characteristics of the host and the pathogen have complicated the vaccine development. This review summarizes the current state of vaccine development for this ubiquitous pathogen, in particular to provide mucosal immunity against infections of the respiratory tract in susceptible individuals with cystic fibrosis.

Indexed as

AnimalsBiomedical ResearchClinical Trials as TopicCystic FibrosisDisease Models, AnimalDrug Evaluation, PreclinicalHumansImmunity, MucosalImmunocompromised HostPseudomonas aeruginosaPseudomonas InfectionsPseudomonas VaccinesPseudomonas Vaccines

Identifiers

PMID21941090
PMCPMC3360073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.