Evidence map›Paper›PMID 21940923›Full record

ArticleAmerican journal of public health2012

Impact of introducing the pneumococcal and rotavirus vaccines into the routine immunization program in Niger.

Bruce Y Lee, Tina-Marie Assi, Jayant Rajgopal, Bryan A Norman, Sheng-I Chen, Shawn T Brown, Rachel B Slayton, Souleymane Kone, Hailu Kenea, Joel S Welling and 6 more

Open access · greenAbstract read
In one paragraph

Article in American journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 47 citations in OpenAlex.

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  15. Economics and financing of vaccines for diarrheal diseases.Human vaccines & immunotherapeutics · 2014
    Review
  16. Article
  17. Article
  18. Prevention of influenza in healthy children.Expert review of anti-infective therapy · 2012
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Bruce Y LeeUniversity of Pittsburgh, Pittsburgh, PA 15213, USA. BYL1@pitt.edu
Tina-Marie Assi
Jayant Rajgopal
Bryan A Norman
Sheng-I Chen
Shawn T Brown
Rachel B Slayton
Souleymane Kone
Hailu Kenea
Joel S Welling
Diana L Connor
Angela R Wateska
Anirban Jana
Ann E Wiringa
Willem G Van Panhuis
Donald S Burke
World Health Organization · CH

Funding

Training, Outreach & Diversity ComponentU54GM088491 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAKOSKI, JOAN M · 2009 to 2018
$16.7M
NIGMS NIH HHS 1U54GM088491-0109NIGMS NIH HHS U54 GM088491
6 · The paper itself

Abstract

objectivesWe investigated whether introducing the rotavirus and pneumococcal vaccines, which are greatly needed in West Africa, would overwhelm existing supply chains (i.e., the series of steps required to get a vaccine from the manufacturers to the target population) in Niger.

methodsAs part of the Bill and Melinda Gates Foundation-funded Vaccine Modeling Initiative, we developed a computational model to determine the impact of introducing these new vaccines to Niger's Expanded Program on Immunization vaccine supply chain.

resultsIntroducing either the rotavirus vaccine or the 7-valent pneumococcal conjugate vaccine could overwhelm available storage and transport refrigerator space, creating bottlenecks that would prevent the flow of vaccines down to the clinics. As a result, the availability of all World Health Organization Expanded Program on Immunization vaccines to patients might decrease from an average of 69% to 28.2% (range = 10%-51%). Addition of refrigerator and transport capacity could alleviate this bottleneck.

conclusionsOur results suggest that the effects on the vaccine supply chain should be considered when introducing a new vaccine and that computational models can help assess evolving needs and prevent problems with vaccine delivery.

Indexed as

Computer SimulationDrug StorageHeptavalent Pneumococcal Conjugate VaccineHumansImmunization ProgramsNigerPneumococcal VaccinesRefrigerationRotavirus VaccinesTransportationVaccines, AttenuatedWorld Health OrganizationHeptavalent Pneumococcal Conjugate VaccinePneumococcal VaccinesRIX4414 vaccineRotaTeqRotavirus VaccinesVaccines, Attenuated

Identifiers

PMID21940923
PMCPMC3386610
OpenAlexW2075552387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.