ArticleAmerican journal of public health2012
Effectiveness of the targeted hepatitis B vaccination program in Greenland.
Article in American journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 25 citations in OpenAlex.
- Evaluation of hepatitis B vaccine effectiveness among fully vaccinated healthcare workers in Ethiopia.BMC infectious diseases · 2025Article
- Breakthrough hepatitis B virus infection and its associated factors among vaccinated children in Northwest Ethiopia.Scientific reports · 2025Article
- Reduced protective efficacy of hepatitis B vaccine among fully vaccinated children in Ethiopia.PloS one · 2023Article
- Article
- Selective Hepatitis B Birth-Dose Vaccination in São Tomé and Príncipe: A Program Assessment and Cost-Effectiveness Study.The American journal of tropical medicine and hygiene · 2019Article
- Implementing a Birth Dose of Hepatitis B Vaccine in Africa: Findings from Assessments in 5 Countries.Journal of immunological sciences · 2018Article
- The status of hepatitis B control in the African region.The Pan African medical journal · 2017Review
- Hepatitis B virus infection among pregnant women in Haiti: A cross-sectional serosurvey.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Article
- Hepatitis B virus: where do we stand and what is the next step for eradication?World journal of gastroenterology · 2014Review
- Burden and prevention of viral hepatitis in the Arctic region, Copenhagen, Denmark, 22-23 March 2012.International journal of circumpolar health · 2013Article
- The Arctic Human Health Initiative: a legacy of the International Polar Year 2007-2009.International journal of circumpolar health · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the effectiveness of the hepatitis B virus (HBV) vaccination program in Greenland, which targets children born to mothers who are positive for HBV surface antigen (HBsAg), we determined vaccination coverage, levels of postvaccination antibodies, and frequency of breakthrough infections in at-risk children.
methodsWe conducted a population-based retrospective cohort study with data from nationwide registries. We identified all children born to HBsAg-positive mothers from 1992 to 2007 and collected data on their HBV vaccination status. In 2008 to 2010, we tested the children for HBV core antibody, HBsAg, and anti-HBsAg antibody (HBsAb).
resultsOf 4050 pregnant women, 3.2% were HBsAg positive. Of 207 children born to these women, 20% received no vaccinations, and only 58% received at least 3 vaccinations. At follow-up, HBsAb levels in vaccinated children were much lower than expected, and 8 (6%) of 140 at-risk children had breakthrough infections, with 4 chronically infected (persistently HBsAg positive).
conclusionsThe prevention program targeting children at risk for HBV in Greenland is ineffective. HBV vaccination should be included in the universal childhood vaccination program, and postvaccination HBsAb levels should be monitored.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.