Evidence map›Paper›PMID 21940856›Full record

ArticleScience (New York, N.Y.)2011

An Aboriginal Australian genome reveals separate human dispersals into Asia.

Morten Rasmussen, Xiaosen Guo, Yong Wang, Kirk E Lohmueller, Simon Rasmussen, Anders Albrechtsen, Line Skotte, Stinus Lindgreen, Mait Metspalu, Thibaut Jombart and 48 more

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
273citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

273 citing papers in PubMed, 1 synthesis or guideline pooled it.

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213 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

58 authors.

Morten RasmussenCentre for GeoGenetics, Natural History Museum of Denmark, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.
Xiaosen Guo
Yong Wang
Kirk E Lohmueller
Simon Rasmussen
Anders Albrechtsen
Line Skotte
Stinus Lindgreen
Mait Metspalu
Thibaut Jombart
Toomas Kivisild
Weiwei Zhai
Anders Eriksson
Andrea Manica
Ludovic Orlando
Francisco M De La Vega
Silvana Tridico
Ene Metspalu
Kasper Nielsen
María C Ávila-Arcos
J Víctor Moreno-Mayar
Craig Muller
Joe Dortch
M Thomas P Gilbert
Ole Lund
Agata Wesolowska
Monika Karmin
Lucy A Weinert
Bo Wang
Jun Li
Shuaishuai Tai
Fei Xiao
Tsunehiko Hanihara
George van Driem
Aashish R Jha
François-Xavier Ricaut
Peter de Knijff
Andrea B Migliano
Irene Gallego Romero
Karsten Kristiansen
David M Lambert
Søren Brunak
Peter Forster
Bernd Brinkmann
Olaf Nehlich
Michael Bunce
Michael Richards
Ramneek Gupta
Carlos D Bustamante
Anders Krogh
Robert A Foley
Marta M Lahr
Francois Balloux
Thomas Sicheritz-Pontén
Richard Villems
Rasmus Nielsen
Jun Wang
Eske Willerslev

Funding

Population Genetic Inferences From Dense Genotype DataR01HG003229 · NHGRI · CORNELL UNIVERSITY ITHACA · PI BUSTAMANTE, CARLOS DANIEL, CLARK, ANDREW G · 2004 to 2013
$4.8M
Biotechnology and Biological Sciences Research Council BB/H005854/1Biotechnology and Biological Sciences Research Council BB/H008802/1NHGRI NIH HHS R01 HG003229
6 · The paper itself

Abstract

We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.

Indexed as

Genome, HumanAnimalsAsiaAsia, EasternAsian PeopleBlack PeopleComputer SimulationDNA, MitochondrialEmigration and ImmigrationEthnicityGene FlowGene FrequencyGenetics, PopulationGenome, MitochondrialHaplotypesHominidaeDNA, Mitochondrial

Identifiers

PMID21940856
PMCPMC3991479

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.