SynthesisClinical journal of the American Society of Nephrology : CJASN2011
Pregnancy outcomes in women with chronic kidney disease: a systematic review.
Synthesis in Clinical journal of the American Society of Nephrology : CJASN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 8 syntheses or guidelines pooled it, 242 citations in OpenAlex.
- Pregnancy occurring in AA amyloidosis: a series of 27 patients including 3 new French cases.Journal of nephrology · 2024Pooled it
- Thoracic organ transplantation and pregnancy outcomes: systematic review and meta-analysis.Archives of gynecology and obstetrics · 2024Pooled it
- Clinical practice guideline on pregnancy and renal disease.BMC nephrology · 2019Guideline
- A best-practice position statement on pregnancy after kidney transplantation: focusing on the unsolved questions. The Kidney and Pregnancy Study Group of the Italian Society of Nephrology.Journal of nephrology · 2018Guideline
- A best practice position statement on the role of the nephrologist in the prevention and follow-up of preeclampsia: the Italian study group on kidney and pregnancy.Journal of nephrology · 2017Guideline
- A Systematic Review and Meta-Analysis of Outcomes of Pregnancy in CKD and CKD Outcomes in Pregnancy.Clinical journal of the American Society of Nephrology : CJASN · 2015Pooled it
- Adiposity has a greater impact on hypertension in lean than not-lean populations: a systematic review and meta-analysis.European journal of epidemiology · 2014Pooled it
- Type 1 diabetes, diabetic nephropathy, and pregnancy: a systematic review and meta-study.The review of diabetic studies : RDS · 2013Pooled it
- Donor medicine: An emerging field in nephrology.World journal of nephrology · 2026Review
- Reproductive Planning and Preconception Counseling in Kidney Disease (REPKID):A Cross-Sectional Survey.Kidney medicine · 2026Article
- Multifetal Pregnancies in Women with CKD: Risk Assessment and Indications for Counseling.Kidney360 · 2026Article
- Pregnancy outcomes and risk factors analysis in patients with chronic kidney disease: a nested case-control study.BMC pregnancy and childbirth · 2026Article
- Navigating Pregnancy With Primary Glomerular Disease: Experience From a Lower-Middle-Income Country.Kidney medicine · 2026Article
- Acute kidney injury requiring temporary hemodialysis due to HELLP syndrome: a case report.CEN case reports · 2026Article
- Overview of ADPKD in Pregnancy.Kidney international reports · 2025Review
- Recurrence of preeclampsia is common, even during rigorously controlled multidisciplinary follow-up: a pilot experience.Clinical kidney journal · 2025Article
- Kidney disease and reproductive health.Nature reviews. Nephrology · 2025Review
- Anesthesia Management in Antenatal Care for Women With Chronic Kidney Disease: A Comprehensive Review.Cureus · 2024Review
- Risk factors for preeclampsia in patients with chronic kidney disease primarily focused on stage 1 CKD. Are referred and registered patients alike?Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Pre-gestational counselling for women living with CKD: starting from the bright side.Clinical kidney journal · 2024Review
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 5 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectivesPregnant women with chronic kidney disease (CKD) are at risk of adverse maternal and fetal outcomes. We conducted a systematic review of observational studies that described this risk. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We searched several databases from their date of inception through June 2010 for eligible articles published in any language. We included any study that reported maternal or fetal outcomes in at least five pregnant women in each group with or without CKD. We excluded pregnant women with a history of transplantation or maintenance dialysis.
resultsWe identified 13 studies. Adverse maternal events including gestational hypertension, pre-eclampsia, eclampsia, and maternal mortality were reported in 12 studies. There were 312 adverse maternal events among 2682 pregnancies in women with CKD (weighted average of 11.5%) compared with 500 events in 26,149 pregnancies in normal healthy women (weighted average of 2%). One or more adverse fetal outcomes such as premature births, intrauterine growth restriction, small for gestational age, neonatal mortality, stillbirths, and low birth weight were reported in nine of the included studies. Overall, the risk of developing an adverse fetal outcome was at least two times higher among women with CKD compared with those without.
conclusionsThis review summarizes current available evidence to guide physicians in their decision-making, advice, and care for pregnant women with CKD. Additional studies are needed to better characterize the risks.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.