ArticleAmerican journal of epidemiology2011
Associations of birth order with early growth and adolescent height, body composition, and blood pressure: prospective birth cohort from Brazil.
Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation.Communications biology · 2024Pooled it
- The Maternal Capital Hypothesis: Giving Mothers Central Place in Evolutionary Perspectives on Developmental Plasticity and Health.American journal of human biology : the official journal of the Human Biology Council · 2025Review
- Lessons from 13 years of accelerometry measurements in five Brazilian cohorts: methodological aspects.Cadernos de saude publica · 2025Article
- Observational
- Article
- Differential gene expression in two consecutive pregnancies between same sex siblings and implications on maternal constraint.Scientific reports · 2024Article
- Relationship between Birth Order and Postnatal Growth until 4 Years of Age: The Japan Environment and Children's Study.Children (Basel, Switzerland) · 2023Article
- Is only-child status associated with a higher blood pressure in adolescence? An observational study.European journal of pediatrics · 2023Observational
- Exploring the Associations between Single-Child Status and Childhood High Blood Pressure and the Mediation Effect of Lifestyle Behaviors.Nutrients · 2022Article
- Sex Differences in the Association of Sibship Size and Position in Sibship with Lipid Profile during Adolescence: A Cross-Sectional Study.International journal of endocrinology · 2022Article
- Influence of Maternal Active and Secondhand Smoking during Pregnancy on Childhood Obesity at 3 Years of Age: A Nested Case-Control Study from the Japan Environment and Children's Study (JECS).International journal of environmental research and public health · 2021Article
- Inequity in health care utilization for common childhood illnesses in India: measurement and decomposition analysis using the India demographic and health survey 2015-16.BMC health services research · 2021Article
- [Family functioning, parental rearing and its relationship to nutritional status in preschoolers].Atencion primaria · 2020Article
- Association of number of siblings, birth order, and thinness in 3- to 12-year-old children: a population-based cross-sectional study in Shanghai, China.BMC pediatrics · 2020Article
- Campylobacter infection and household factors are associated with childhood growth in urban Bangladesh: An analysis of the MAL-ED study.PLoS neglected tropical diseases · 2020Article
- Associations of fat mass and fat-free mass accretion in infancy with body composition and cardiometabolic risk markers at 5 years: The Ethiopian iABC birth cohort study.PLoS medicine · 2019Article
- Adjustment for time-invariant and time-varying confounders in 'unexplained residuals' models for longitudinal data within a causal framework and associated challenges.Statistical methods in medical research · 2019Article
- Developmental plasticity as adaptation: adjusting to the external environment under the imprint of maternal capital.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Review
- The differences of lipid profiles between only children and children with siblings: A national survey in China.Scientific reports · 2019Article
- Associations of stunting at 2 years with body composition and blood pressure at 8 years of age: longitudinal cohort analysis from lowland Nepal.European journal of clinical nutrition · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Birth weight has been inversely associated with later blood pressure. Firstborns tend to have lower birth weight than their later-born peers, but the long-term consequences remain unclear. The study objective was to investigate differences between firstborn and later-born individuals in early growth patterns, body composition, and blood pressure in Brazilian adolescents. The authors studied 453 adolescents aged 13.3 years from the prospective 1993 Pelotas Birth Cohort. Anthropometry, blood pressure, physical activity by accelerometry, and body composition by deuterium were measured. Firstborns (n = 143) had significantly lower birth weight than later borns (n = 310). At 4 years, firstborns had significantly greater weight and height, indicating a substantial overshoot in catch-up growth. In adolescence, first borns had significantly greater height and blood pressure and a lower activity level. The difference in systolic blood pressure could be attributed to variability in early growth and that in diastolic blood pressure to reduced physical activity. The magnitude of increased blood pressure is clinically significant; hence, birth order is an important developmental predictor of cardiovascular risk in this population. Firstborns may be more sensitive to environmental factors that promote catch-up growth, and this information could potentially be used in nutritional management to prevent catch-up "overshoot."
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.