ArticleGenome biology and evolution2011
Short- and long-term evolutionary dynamics of bacterial insertion sequences: insights from Wolbachia endosymbionts.
Article in Genome biology and evolution, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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39 citing papers in PubMed, 66 citations in OpenAlex.
- Genomic islands in Wolbachia prophages drive amplification and diversification of cytoplasmic incompatibility genes in Culex pipiens.Genetics · 2026Article
- Calibrating and documenting host-switching and evolution of incompatibility loci for two closely related Wolbachia clades.Genetics · 2026Article
- Within-Host Environmental Heterogeneity Is Associated With Phenotypic but Not Genomic Diversity in Wolbachia Endosymbionts.Environmental microbiology reports · 2026Article
- Article
- Complete De Novo Assembly ofInternational journal of molecular sciences · 2023Article
- Complicated expansion trajectories of insertion sequences and potential association with horizontal transfer ofZoological research · 2023Article
- Widespread phages of endosymbionts: Phage WO genomics and the proposed taxonomic classification of Symbioviridae.PLoS genetics · 2022Article
- Article
- Genomic Analysis of Wolbachia from Laodelphax striatellus (Delphacidae, Hemiptera) Reveals Insights into Its "Jekyll and Hyde" Mode of Infection Pattern.Genome biology and evolution · 2020Article
- The Wolbachia mobilome in Culex pipiens includes a putative plasmid.Nature communications · 2019Article
- Complete Genome Sequence of the Wolbachia wAlbB Endosymbiont of Aedes albopictus.Genome biology and evolution · 2019Article
- Genome expansion of an obligate parthenogenesis-associated Wolbachia poses an exception to the symbiont reduction model.BMC genomics · 2019Article
- Influence of ISAntimicrobial agents and chemotherapy · 2017Article
- Disentangling the effects of selection and loss bias on gene dynamics.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Mixed transmission modes and dynamic genome evolution in an obligate animal-bacterial symbiosis.The ISME journal · 2017Article
- Endozoicomonas genomes reveal functional adaptation and plasticity in bacterial strains symbiotically associated with diverse marine hosts.Scientific reports · 2017Article
- Inevitability of Genetic Parasites.Genome biology and evolution · 2016Article
- Review
- Comparative Genomics of Two Closely Related Wolbachia with Different Reproductive Effects on Hosts.Genome biology and evolution · 2016Article
- Supergroup C Wolbachia, mutualist symbionts of filarial nematodes, have a distinct genome structure.Open biology · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transposable elements (TE) are one of the major driving forces of genome evolution, raising the question of the long-term dynamics underlying their evolutionary success. Long-term TE evolution can readily be reconstructed in eukaryotes, thanks to many degraded copies constituting genomic fossil records of past TE proliferations. By contrast, bacterial genomes usually experience high sequence turnover and short TE retention times, thereby obscuring ancient TE evolutionary patterns. We found that Wolbachia bacterial genomes contain 52-171 insertion sequence (IS) TEs. IS account for 11% of Wolbachia wRi, which is one of the highest IS genomic coverage reported in prokaryotes to date. We show that many IS groups are currently expanding in various Wolbachia genomes and that IS horizontal transfers are frequent among strains, which can explain the apparent synchronicity of these IS proliferations. Remarkably, >70% of Wolbachia IS are nonfunctional. They constitute an unusual bacterial IS genomic fossil record providing direct empirical evidence for a long-term IS evolutionary dynamics following successive periods of intense transpositional activity. Our results show that comprehensive IS annotations have the potential to provide new insights into prokaryote TE evolution and, more generally, prokaryote genome evolution. Indeed, the identification of an important IS genomic fossil record in Wolbachia demonstrates that IS elements are not always of recent origin, contrary to the conventional view of TE evolution in prokaryote genomes. Our results also raise the question whether the abundance of IS fossils is specific to Wolbachia or it may be a general, albeit overlooked, feature of prokaryote genomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.