Evidence map›Paper›PMID 21940468›Full record

ArticleJournal of clinical microbiology2011

Target-specific capture enhances sensitivity of electrochemical detection of bacterial pathogens.

Mayank Patel, Rodrigo Gonzalez, Colin Halford, Michael A Lewinski, Elliot M Landaw, Bernard M Churchill, David A Haake

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Bacterial detection & identification using electrochemical sensors.Journal of visualized experiments : JoVE · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mayank PatelDepartment of Urology, The David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.
Rodrigo Gonzalez
Colin Halford
Michael A Lewinski
Elliot M Landaw
Bernard M Churchill
David A Haake

Funding

Sensor Technology for Rapid Microbial Identification and Susceptibility TestingU01AI075565 · NIAID · BRENTWOOD BIOMEDICAL RESEARCH INSTITUTE · PI HAAKE, DAVID A · 2007 to 2011
$3.3M
NIAID NIH HHS AI075565NIAID NIH HHS U01 AI075565
6 · The paper itself

Abstract

We report the concentration and purification of bacterial 16S rRNA by the use of a biotinylated DNA target-specific capture (TSC) probe. For both cultivated bacterial and urine specimens from urinary tract infection patients, TSC resulted in a 5- to 8-fold improvement in the sensitivity of bacterial detection in a 16S rRNA electrochemical sensor assay.

Indexed as

Oligonucleotide ProbesBacteriaBacteriological TechniquesBiosensing TechniquesElectrochemical TechniquesHumansRNA, Ribosomal, 16SSensitivity and SpecificityUrineOligonucleotide ProbesRNA, Ribosomal, 16S

Identifiers

PMID21940468
PMCPMC3232961

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.