ArticleCanadian journal of surgery. Journal canadien de chirurgie2011
Total pelvic exenteration for rectal cancer: outcomes and prognostic factors.
Article in Canadian journal of surgery. Journal canadien de chirurgie, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review of oncosurgical and quality of life outcomes following pelvic exenteration for locally advanced and recurrent rectal cancer.Annals of the Royal College of Surgeons of England · 2025Pooled it
- A systematic review and meta-analysis on mortality rate following total pelvic exenteration in cancer patients.BMC cancer · 2024Pooled it
- A Systematic Review on Overall Survival and Disease-Free Survival Following Total Pelvic Exenteration.Asian Pacific journal of cancer prevention : APJCP · 2022Pooled it
- Outcomes and survival trends following pelvic exenteration for locally advanced and recurrent rectal cancer: a 20-Year analysis from a tertiary cancer center in India.World journal of surgical oncology · 2025Article
- Review
- Robotic versus open and laparoscopic pelvic exenterations for pelvic cancer: a multicenter propensity-matched analysis in Japan.Surgical endoscopy · 2024Article
- Surgical outcomes in pelvic exenteration for advanced and recurrent malignancy: a high volume single institution experience.Langenbeck's archives of surgery · 2023Article
- Diagnostic performance ofAbdominal radiology (New York) · 2021Article
- Review of incomplete macroscopic resections (R2) in rectal cancer: Treatment, prognosis and future perspectives.World journal of gastrointestinal oncology · 2021Review
- FDG-PET/MRI in patients with pelvic recurrence of rectal cancer: first clinical experiences.European radiology · 2019Article
- Efficacy of an additional flap operation in bladder-preserving surgery with radical prostatectomy and cystourethral anastomosis for rectal cancer involving the prostate.Surgery today · 2017Article
- Layer-oriented total pelvic exenteration for locally advanced primary colorectal cancer.International journal of colorectal disease · 2016Article
- Outcomes of pelvic exenteration for recurrent or primary locally advanced colorectal cancer.Annals of surgical treatment and research · 2015Article
- Pelvic exenteration: experience from a rural cancer center in developing world.International journal of surgical oncology · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo perform complete resection of locally advanced and recurrent rectal carcinoma, total pelvic exenteration (TPE) may be attempted. We identified disease-related outcomes and prognostic factors.
methodsWe conducted a single-centre review of patients who underwent TPE for rectal carcinoma over a 10-year period.
resultsWe included 28 patients in our study. After a median follow-up of 35 months, 53.6% of patients were alive with no evidence of disease. The 3-year actuarial disease-free and overall survival rates were 52.2% and 75.1%, respectively. On univariate analysis, recurrent disease, preoperative body mass index greater than 30 and lymphatic invasion were poor prognostic factors for disease-free survival, and only lymphatic invasion predicted overall survival. Additionally, multivariate analysis identified lymphatic invasion as an independent poor prognostic factor for disease-free survival in this patient population with locally advanced and recurrent rectal carcinoma.
conclusionDespite the significant morbidity, TPE can provide long-term survival in patients with rectal carcinoma. Additionally, lymphatic invasion on final pathology was an independent prognostic factor for disease-free survival.
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